Vertex Pharmaceuticals Pharmaceuticals — income (loss) increased by 10.0% to $1.19B in Q4 2025 compared to the prior quarter. Over 2 years (FY 2022 to FY 2025), Pharmaceuticals — income (loss) shows an upward trend with a 9.1% CAGR. This is a positive signal — higher values indicate stronger performance for this metric.
An increase indicates improved operational efficiency or stronger product demand, while a decrease may signal rising R&D costs, commercialization investments, or competitive pressure on drug pricing.
This metric represents the operating profitability of the core pharmaceutical business segment after accounting for all...
Comparable to operating income or segment profit reported by other large-cap biotechnology and pharmaceutical companies, though variations exist based on how firms allocate R&D and corporate overhead.
vrtx_segment_pharmaceuticals_income_loss| Q1 '22 | Q2 '22 | Q3 '22 | Q4 '22 | Q1 '23 | Q2 '23 | Q3 '23 | Q4 '23 | Q1 '24 | Q2 '24 | Q3 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Value | $830.50M | $830.50M | $830.50M | $830.50M | $904.90M | $904.90M | $904.90M | $904.90M | $1.10B | -$3.59B | $1.05B | $646.30M | $1.03B | $1.08B | $1.19B |
| QoQ Change | — | +0.0% | +0.0% | +0.0% | +9.0% | +0.0% | +0.0% | +0.0% | +21.5% | -426.8% | +129.1% | -38.2% | +59.8% | +4.8% | +10.0% |
| YoY Change | — | — | — | — | +9.0% | +9.0% | +9.0% | +9.0% | +21.5% | -497.1% | +15.5% | -41.2% | +128.7% | +3.6% | — |
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