Business Segments · income (loss)

Pharmaceuticals — income (loss)

Vertex Pharmaceuticals Pharmaceuticals — income (loss) increased by 10.0% to $1.19B in Q4 2025 compared to the prior quarter. Over 2 years (FY 2022 to FY 2025), Pharmaceuticals — income (loss) shows an upward trend with a 9.1% CAGR. This is a positive signal — higher values indicate stronger performance for this metric.

Analysis

StatementSegment
CategoryProfitability
SignalHigher is better
VolatilityModerate
First reportedQ1 2022
Last reportedQ4 2025
Rolls up toNet Income

How to read this metric

An increase indicates improved operational efficiency or stronger product demand, while a decrease may signal rising R&D costs, commercialization investments, or competitive pressure on drug pricing.

Detailed definition

This metric represents the operating profitability of the core pharmaceutical business segment after accounting for all...

Peer comparison

Comparable to operating income or segment profit reported by other large-cap biotechnology and pharmaceutical companies, though variations exist based on how firms allocate R&D and corporate overhead.

Metric ID: vrtx_segment_pharmaceuticals_income_loss

Historical Data

15 periods
 Q1 '22Q2 '22Q3 '22Q4 '22Q1 '23Q2 '23Q3 '23Q4 '23Q1 '24Q2 '24Q3 '24Q1 '25Q2 '25Q3 '25Q4 '25
Value$830.50M$830.50M$830.50M$830.50M$904.90M$904.90M$904.90M$904.90M$1.10B-$3.59B$1.05B$646.30M$1.03B$1.08B$1.19B
QoQ Change+0.0%+0.0%+0.0%+9.0%+0.0%+0.0%+0.0%+21.5%-426.8%+129.1%-38.2%+59.8%+4.8%+10.0%
YoY Change+9.0%+9.0%+9.0%+9.0%+21.5%-497.1%+15.5%-41.2%+128.7%+3.6%
Range-$3.59B$1.19B
CAGR+10.9%
Avg YoY Growth-33.3%
Median YoY Growth+9.0%
Current Streak3 quarters growth

Frequently Asked Questions

What is Vertex Pharmaceuticals's pharmaceuticals — income (loss)?
Vertex Pharmaceuticals (VRTX) reported pharmaceuticals — income (loss) of $1.19B in Q4 2025.
What is the long-term trend for Vertex Pharmaceuticals's pharmaceuticals — income (loss)?
Over 2 years (2022 to 2025), Vertex Pharmaceuticals's pharmaceuticals — income (loss) has grown at a 9.1% compound annual growth rate (CAGR), from $3.32B to $3.95B.
What does pharmaceuticals — income (loss) mean?
The net profit or loss generated specifically by the pharmaceutical business segment after all related operating expenses.

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