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Axsome Therapeutics AXSM Return on equity

Return on equity at other companies

Eli Lilly logo
Eli LillyLLY
107.6%+29.9pp
Johnson & Johnson logo
Johnson & JohnsonJNJ
26.4%-3.0pp
AbbVie logo
AbbVieABBV
89%+32.7pp
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
22.5%+10.1pp
Jazz Pharmaceuticals logo
Jazz PharmaceuticalsJAZZ
-9.1%-21.2pp
Arrowhead Research logo
Arrowhead ResearchARWR
-46.4%+341pp

Other financials

Income statement

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Revenue$191.2M+57.4%
Gross profit$176.5M+58.0%
Operating income-$63.4M-11.2%
Net income-$64.5M-8.6%
EPS (diluted)-$1.26-3.3%

Balance sheet

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Cash & equivalents$305.1M+1.4%
Total debt$219.9M+4.1%
Total equity$54.6M+2.6%
Total assets$713.6M+19.6%

Cash flow

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Operating cash flow-$20.7M+52.3%
CapEx$121.0K-64.2%
Free cash flow-$20.8M+52.4%

Valuation

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Market cap$12.89B+52.0%
Enterprise value$12.81B+52.9%
P/S18.2×-1.4×

Profitability

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Gross margin92.6%+1.1pp
Operating margin-24.4%-9.3pp
Net margin-26.6%-9.8pp
FCF margin-10.2%-3.9pp

Returns & leverage

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Debt / equity+0.1×
Current ratio1.4×-0.6×

Where this comes from

Calculated from Axsome Therapeutics’s reported figures.

Based on trailing twelve months.

The official record: Axsome Therapeutics’s 10-Q, filed May 4, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Axsome Therapeutics's return on equity?
Axsome Therapeutics (AXSM) reported return on equity of -349.4% in Q1 2026.
How has Axsome Therapeutics's return on equity changed year-over-year?
Axsome Therapeutics's return on equity decreased by 23.8% year-over-year, from -282.2% to -349.4%.
What is the long-term trend for Axsome Therapeutics's return on equity?
Over 5 years (2020 to 2025), Axsome Therapeutics's return on equity has grown at a 29.1% compound annual growth rate (CAGR), from -70.4% to -252.1%.
What does return on equity mean?
How much profit the company earns on the money shareholders have invested.
How do you interpret return on equity?
Higher is better, but very high ROE can be manufactured by leverage — a thin equity base inflates the ratio. Read it next to debt-to-equity and ROIC to tell genuine returns from balance-sheet engineering.
How does return on equity compare across companies?
Comparable across peers, with the leverage caveat. Negative or near-zero equity makes ROE meaningless, so it is suppressed there.