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Axsome Therapeutics AXSM Operating margin

Operating margin at other companies

Johnson & Johnson logo
Johnson & JohnsonJNJ
26.4%+2.8pp
AbbVie logo
AbbVieABBV
24.4%
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-90.5%-41.2pp
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
25.4%+4.9pp
Jazz Pharmaceuticals logo
Jazz PharmaceuticalsJAZZ
-11.9%-28.1pp
Arrowhead Research logo
Arrowhead ResearchARWR
-35.7%+63.6pp

Other financials

Income statement

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Revenue$191.2M+57.4%
Gross profit$176.5M+58.0%
Operating income-$63.4M-11.2%
Net income-$64.5M-8.6%
EPS (diluted)-$1.26-3.3%

Balance sheet

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Cash & equivalents$305.1M+1.4%
Total debt$219.9M+4.1%
Total equity$54.6M+2.6%
Total assets$713.6M+19.6%

Cash flow

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Operating cash flow-$20.7M+52.3%
CapEx$121.0K-64.2%
Free cash flow-$20.8M+52.4%

Valuation

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Market cap$12.89B+52.0%
Enterprise value$12.81B+52.9%
P/S18.2×-1.4×

Profitability

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Gross margin92.6%+1.1pp
Net margin-26.6%-9.8pp
FCF margin-10.2%-3.9pp

Returns & leverage

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Return on equity-349.4%+109pp
Debt / equity+0.1×
Current ratio1.4×-0.6×

Where this comes from

Calculated from Axsome Therapeutics’s reported figures.

Based on trailing twelve months.

The official record: Axsome Therapeutics’s 10-Q, filed May 4, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Axsome Therapeutics's operating margin?
Axsome Therapeutics (AXSM) reported operating margin of -24.4% in Q1 2026.
How has Axsome Therapeutics's operating margin changed year-over-year?
Axsome Therapeutics's operating margin increased by 60.9% year-over-year, from -62.5% to -24.4%.
What is the long-term trend for Axsome Therapeutics's operating margin?
Over 3 years (2022 to 2025), Axsome Therapeutics's operating margin has grown at a -58.3% compound annual growth rate (CAGR), from -359.3% to -26.1%.
What does operating margin mean?
The profit left from core operations for every dollar of sales, before interest and taxes.
How do you interpret operating margin?
Expanding operating margin shows operating leverage — revenue growing faster than the cost base. Compression points to rising overhead, pricing pressure, or investment ahead of revenue.
How does operating margin compare across companies?
Strong cross-company signal within a sector. Capital-light businesses sustain higher operating margins than capital-intensive ones.