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Denali Therapeutics Inc. DNLI Net margin

Net margin at other companies

Eli LillyLLY

35%+12.3pp

Regeneron PharmaceuticalsREGN

29.6%-2.3pp

Acadia PharmaceuticalsACAD

34.3%+11.3pp

BridgeBio PharmaBBIO

-125.9%-54.5pp

BiogenBIIB

14.3%-0.8pp

PTC TherapeuticsPTCT

42.3%+27.4pp

Other financials

Income statement

Revenue-—

Operating income-$137.4M+5.6%

Net income-$128.4M+3.4%

EPS (diluted)-$0.69+11.5%

Balance sheet

Cash & equivalents$390.7M+551%

Total debt$40.0M-22.3%

Total equity$926.1M-17.5%

Total assets$1.3B-0.4%

Cash flow

Operating cash flow-$131.2M+0.2%

CapEx$2.5M-51.4%

Free cash flow-$133.7M+2.1%

Valuation

Market cap$3.7B+54.2%

Enterprise value$3.35B+37.1%

Profitability

Operating margin-37,938%-37,986pp

FCF margin-31,736.3%-31,830pp

Returns & leverage

Return on equity-49.6%+34.2pp

Debt / equity0×0.0×

Current ratio9.3×-0.3×

Where this comes from

Calculated from Denali Therapeutics Inc.’s reported figures.

net income/total revenue=-33,121.9%

Based on trailing twelve months.

The official record: Denali Therapeutics Inc.’s 10-Q, filed August 11, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s net margin?: Denali Therapeutics Inc. (DNLI) reported net margin of -33,121.9% in Q2 2024.
How has Denali Therapeutics Inc.'s net margin changed year-over-year?: Denali Therapeutics Inc.'s net margin decreased by 88424.2% year-over-year, from -37.4% to -33,121.9%.
What is the long-term trend for Denali Therapeutics Inc.'s net margin?: Over 3 years (2020 to 2023), Denali Therapeutics Inc.'s net margin has grown at a 27.5% compound annual growth rate (CAGR), from 21.2% to -43.9%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.