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Segments

By product

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Milestone Triggered$25M
Milestone Payment$2.5M0.0%
Option Fee Payment$2.5M+100%

By segment

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Therapeutics Segment$0

Other financials

Income statement

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Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

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Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

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Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

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Market cap$3.92B+88.3%
Enterprise value$3.76B+89.0%
P/S1,089×+1,084×

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 4:08 PM EDT
Fiscal quarter
Q4 FY2026
Calendar quarter
Q4 2026
Accession
0001714899-26-000097
Line itemThree Months Ended June 30, 2026Three Months Ended June 30, 2025Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Revenue:
Product revenue, net$3,604$3,604
Total revenue3,6043,604
Operating expenses:
Cost of goods sold9393
Research and development97,019102,696200,865218,923
Selling, general and administrative36,28332,26769,79461,620
Intangible asset amortization750750

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s total revenue?
Denali Therapeutics Inc. (DNLI) reported total revenue of $3.6M in Q2 2026.
What is the long-term trend for Denali Therapeutics Inc.'s total revenue?
Over 3 years (2021 to 2024), Denali Therapeutics Inc.'s total revenue has grown at a -100.0% compound annual growth rate (CAGR), from $48.66M to $0.
What does total revenue mean?
The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.

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