What is Denali Therapeutics Inc.'s total revenue?

Denali Therapeutics Inc. (DNLI) reported total revenue of $0 in Q4 2025.

What is the long-term trend for Denali Therapeutics Inc.'s total revenue?

Over 4 years (2021 to 2025), Denali Therapeutics Inc.'s total revenue has grown at a -100.0% compound annual growth rate (CAGR), from $48.66M to $0.

What does total revenue mean?

The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.

Denali Therapeutics Inc. DNLI Total Revenue

Discontinued — last reported Q4 '25

Total Revenue at other companies

Eli LillyLLY

$19.8B+55.5%

Regeneron PharmaceuticalsREGN

$3.61B+19.0%

Viking TherapeuticsVKTX

$0—

Acadia PharmaceuticalsACAD

$268.06M+9.7%

BridgeBio PharmaBBIO

$194.52M+66.8%

BiogenBIIB

$2.48B+1.9%

Segments

By product

See full

Milestone Triggered$25M—

Milestone Payment$2.5M0.0%

Option Fee Payment$2.5M+100%

By segment

See full

Therapeutics Segment$0—

Other financials

Income statement

See full

Operating income-$137.4M+5.6%

Net income-$128.4M+3.4%

EPS (diluted)-$0.69+11.5%

Balance sheet

See full

Cash & equivalents$390.7M+551%

Total debt$40.0M-22.3%

Total equity$926.1M-17.5%

Total assets$1.3B-0.4%

Cash flow

See full

Operating cash flow-$131.2M+0.2%

CapEx$2.5M-51.4%

Free cash flow-$133.7M+2.1%

Valuation

See full

Market cap$3.7B+54.2%

Enterprise value$3.35B+37.1%

Profitability

See full

Operating margin-37,938%-37,986pp

Net margin-33,121.9%-33,159pp

FCF margin-31,736.3%-31,830pp

Returns & leverage

See full

Return on equity-49.6%+34.2pp

Debt / equity0×0.0×

Current ratio9.3×-0.3×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:Revenues.

The official record: Denali Therapeutics Inc.’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s total revenue?: Denali Therapeutics Inc. (DNLI) reported total revenue of $0 in Q4 2025.
What is the long-term trend for Denali Therapeutics Inc.'s total revenue?: Over 4 years (2021 to 2025), Denali Therapeutics Inc.'s total revenue has grown at a -100.0% compound annual growth rate (CAGR), from $48.66M to $0.
What does total revenue mean?: The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.