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Operating margin at other companies

Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
24.3%-2.9pp
Acadia Pharmaceuticals logo
Acadia PharmaceuticalsACAD
7.4%-16.2pp
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-90.5%-41.2pp
PTC Therapeutics logo
PTC TherapeuticsPTCT
1.6%-38.7pp
ALN
Alnylam PharmaceuticalsALNY
17.5%+14.4pp
Beam Therapeutics logo
Beam TherapeuticsBEAM
-226.6%-90.5pp

Other financials

Income statement

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Revenue-
Operating income-$137.4M+5.6%
Net income-$128.4M+3.4%
EPS (diluted)-$0.69+11.5%

Balance sheet

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Cash & equivalents$390.7M+551%
Total debt$40.0M-22.3%
Total equity$926.1M-17.5%
Total assets$1.3B-0.4%

Cash flow

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Operating cash flow-$131.2M+0.2%
CapEx$2.5M-51.4%
Free cash flow-$133.7M+2.1%

Valuation

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Market cap$3.7B+54.2%
Enterprise value$3.35B+37.1%

Profitability

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Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-49.6%+34.2pp
Debt / equity0.0×
Current ratio9.3×-0.3×

Where this comes from

Calculated from Denali Therapeutics Inc.’s reported figures.

Based on trailing twelve months.

The official record: Denali Therapeutics Inc.’s 10-Q, filed August 11, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s operating margin?
Denali Therapeutics Inc. (DNLI) reported operating margin of -37,938% in Q2 2024.
How has Denali Therapeutics Inc.'s operating margin changed year-over-year?
Denali Therapeutics Inc.'s operating margin decreased by 79678.2% year-over-year, from -47.6% to -37,938%.
What is the long-term trend for Denali Therapeutics Inc.'s operating margin?
Over 3 years (2020 to 2023), Denali Therapeutics Inc.'s operating margin has grown at a 47.1% compound annual growth rate (CAGR), from 18.7% to -59.5%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.