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Iovance Biotherapeutics, Inc. IOVA Q4 2025 Annual earnings

Reported February 24, 2026 · Before market open

Revenue$86.7MBeat by $6.0M
EPS-$0.18Beat by $0.04
Revenue estimate$80.7M
EPS estimate-$0.22

Next report

Aug 6, 2026 (In 1 week)
Revenue estimate$87.7M
EPS estimate-$0.17

Financials

Q4 2025

Income statement

See full
Revenue$86.8M+17.7%
Gross profit$43.7M+21.6%
Operating income-$73.5M+15.1%
Net income-$71.9M+8.5%

Balance sheet

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Cash & equivalents$163.1M+41.0%
Total debt$48.4M-16.9%
Total equity$698.6M-1.7%
Total assets$913.2M+0.3%

Cash flow

See full
Operating cash flow-$52.6M+28.3%
CapEx$9.3M+124%
Free cash flow-$61.9M+20.1%

Valuation & ratios

Valuation

as of 12/31/25
See full
Market cap$1.08B-51.9%
Enterprise value$969.09M-55.9%
P/S4.1×-9.6×

Profitability

See full
Gross margin31.3%-2.9pp
Operating margin-153.1%-40.9pp
Net margin-148.4%-38.1pp
FCF margin-127.6%-38.1pp

Returns & leverage

See full
Return on equity-55.5%-1.8pp
Debt / equity0.1×0.0×
Current ratio3.2×-0.5×

Segments

By product

See full
Amtagvi$64.9M+33.2%
Proleukin$21.9M-12.4%

By segment

See full
Single Reportable$86.8M+17.7%

Versus estimates

Revenue

Q1 2026$71.4MMiss by $6.4M
Q4 2025$86.7MBeat by $6.0M
Q3 2025$67.5MMiss by $14.7MQ2 2025$60.0MMiss by $18.4MQ1 2025$49.3MMiss by $33.1MQ4 2024$73.7MBeat by $1.5M

Diluted EPS

Q1 2026-$0.19In line
Q4 2025-$0.18Beat by $0.04
Q3 2025-$0.25Beat by $0.04Q2 2025-$0.33Miss by $0.04Q1 2025-$0.36Miss by $0.11Q4 2024-$0.26In line

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Questions, answered.

When did Iovance Biotherapeutics, Inc. report Q4 2025 earnings?
Iovance Biotherapeutics, Inc. (IOVA) reported Q4 2025 earnings on February 24, 2026 before market open.
What were Iovance Biotherapeutics, Inc.'s Q4 2025 revenue and EPS?
Iovance Biotherapeutics, Inc. reported revenue of $86.7M and eps of $-0.18 for Q4 2025.
Did Iovance Biotherapeutics, Inc. beat estimates in Q4 2025?
Revenue beat the consensus estimate of $80.7M by $6.0M. EPS beat the consensus estimate of $-0.22 by $0.04.
How did Iovance Biotherapeutics, Inc.'s Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 17.7% from $73.7M a year earlier and eps grew 30.8% from $-0.26.
Where can I find Iovance Biotherapeutics, Inc.'s Q4 2025 SEC filings?
You can read the 8-K earnings release (0001104659-26-018837) and the 10-K periodic report (0001104659-26-018899) directly on SEC EDGAR. The filing index links above go to sec.gov.