Operating Income
Gross Profit
Pfizer Gross Profit decreased by 1.6% to $12.29B in Q4 2025 compared to the prior quarter. Year-over-year, this metric grew by 3.6%, from $11.85B to $12.29B. Over 4 years (FY 2021 to FY 2025), Gross Profit shows relatively stable performance with a -2.0% CAGR. This decline may warrant attention — for this metric, higher values are generally preferred.
Analysis
StatementIncome Statement
SectionOperating Income
CategoryProfitability
SignalHigher is better
VolatilityStable
First reportedQ1 2013
Last reportedQ1 2026
How to read this metric
Higher gross profit indicates a strong ability to command premium pricing and manage production costs effectively.
Detailed definition
The profit a company makes after deducting the costs associated with making and selling its products, or the costs assoc...
Peer comparison
Premium hardware brands aim for higher gross profit margins than commodity electronics manufacturers.
Metric ID:
is_gross_profitHistorical Data
19 periods
| Q2 '21 | Q3 '21 | Q4 '21 | Q1 '22 | Q2 '22 | Q3 '22 | Q4 '22 | Q1 '23 | Q2 '23 | Q3 '23 | Q4 '23 | Q1 '24 | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Value | $11.93B | $14.12B | $14.05B | $15.68B | $19.09B | $16.58B | $14.64B | $13.40B | $9.50B | $3.96B | $6.69B | $11.50B | $9.98B | $12.44B | $11.85B | $10.87B | $10.88B | $12.48B | $12.29B |
| QoQ Change | — | +18.4% | -0.5% | +11.6% | +21.8% | -13.2% | -11.7% | -8.5% | -29.1% | -58.3% | +68.7% | +72.0% | -13.2% | +24.6% | -4.7% | -8.3% | +0.0% | +14.8% | -1.6% |
| YoY Change | — | — | — | — | +60.1% | +17.4% | +4.2% | -14.5% | -50.3% | -76.1% | -54.3% | -14.2% | +5.1% | +213.9% | +77.3% | -5.5% | +8.9% | +0.3% | +3.6% |
Range$3.96B – $19.09B
CAGR+0.7%
Avg YoY Growth+11.7%
Median YoY Growth+3.6%
Gross Profit at Other Companies
Frequently Asked Questions
- What is Pfizer's gross profit?
- Pfizer (PFE) reported gross profit of $12.29B in Q4 2025.
- How has Pfizer's gross profit changed year-over-year?
- Pfizer's gross profit increased by 3.6% year-over-year, from $11.85B to $12.29B.
- What is the long-term trend for Pfizer's gross profit?
- Over 4 years (2021 to 2025), Pfizer's gross profit has grown at a -2.0% compound annual growth rate (CAGR), from $50.47B to $46.51B.
- What does gross profit mean?
- The money left over from sales after paying for the direct cost of goods sold.