Skip to content
Screener

Personalis, Inc. PSNL Q4 2025 Annual earnings

Reported February 26, 2026 · After market close

Revenue$17.3MBeat by $295.7K
EPS-$0.26Beat by $0.05
Revenue estimate$17.0M
EPS estimate-$0.31

Next report

Nov 3, 2026 (in 2 months)
Revenue estimate$21.5M
EPS estimate-$0.26

Financials

Q4 2025

Income statement

See full
Revenue$17.3M+3.2%
Gross profit$1.9M-58.2%
Operating income-$25.3M-39.5%
Net income-$23.8M-45.0%
EPS (diluted)-$0.26-44.4%

Balance sheet

See full
Cash & equivalents$124.2M+35.9%
Total debt$42.0M-1.5%
Total equity$261.2M+28.7%
Total assets$334.2M+23.6%

Cash flow

See full
Operating cash flow-$22.2M-185%
CapEx$77.0K-93.8%
Free cash flow-$22.3M-147%

Valuation & ratios

Valuation

as of 12/31/25
See full
Market cap$706.88M+44.4%
Enterprise value$624.6M+41.7%
P/S10.1×+4.4×

Profitability

See full
Gross margin22.7%-9.1pp
Operating margin-126.4%+166pp
Net margin-116.7%+31.9pp
FCF margin-114.1%-1,882pp

Returns & leverage

See full
Return on equity-35%-7.7pp
Debt / equity0.2×0.0×
Current ratio6.8×+0.2×

FAQ

When did Personalis, Inc. report Q4 2025 earnings?
Personalis, Inc. (PSNL) reported Q4 2025 earnings on February 26, 2026 after market close.
What were Personalis, Inc.'s Q4 2025 revenue and EPS?
Personalis, Inc. reported revenue of $17.3M and eps of $-0.26 for Q4 2025.
Did Personalis, Inc. beat estimates in Q4 2025?
Revenue beat the consensus estimate of $17.0M by $295.7K. EPS beat the consensus estimate of $-0.31 by $0.05.
How did Personalis, Inc.'s Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 3.2% from $16.8M a year earlier and eps declined 13.0% from $-0.23.
Where can I find Personalis, Inc.'s Q4 2025 SEC filings?
You can read the 8-K earnings release (0001193125-26-076553) and the 10-K periodic report (0001193125-26-076615) directly on SEC EDGAR. The filing index links above go to sec.gov.