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Personalis, Inc. PSNL Return on invested capital

Return on invested capital at other companies

Quest Diagnostics logo
Quest DiagnosticsDGX
9.2%+0.4pp
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NeoGenomicsNEO
-15.7%+2.0pp
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IlluminaILMN
19.6%
Veracyte logo
VeracyteVCYT
7.1%+4.7pp
Guardant Health logo
Guardant HealthGH
-132.8%
Natera, Inc. logo
Natera, Inc.NTRA
-46.7%-4.0pp

Other financials

Income statement

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Revenue$15.5M-24.9%
Gross profit$281.0K-96.1%
Operating income-$32.2M-81.7%
Net income-$30.0M-90.7%
EPS (diluted)-$0.29-61.1%

Balance sheet

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Cash & equivalents$73.6M+3.7%
Total debt$39.0M-6.2%
Total equity$254.8M+22.9%
Total assets$325.4M+19.1%

Cash flow

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Operating cash flow-$22.5M-25.1%
CapEx$3.2M+27.1%
Free cash flow-$25.7M-25.4%

Valuation

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Market cap$1.19B+110%
Enterprise value$1.16B+115%
P/S18.4×+11.8×

Profitability

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Gross margin13.7%-19.6pp
Operating margin-158.9%-5,457pp
Net margin-148.1%+154pp
FCF margin-131.2%-453pp

Returns & leverage

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Return on equity-41.4%-6.7pp
Debt / equity0.2×0.0×
Current ratio6.6×-0.3×

Where this comes from

Calculated from Personalis, Inc.’s reported figures.

Based on trailing twelve months.

The official record: Personalis, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Personalis, Inc.'s return on invested capital?
Personalis, Inc. (PSNL) reported return on invested capital of -51.5% in Q1 2026.
How has Personalis, Inc.'s return on invested capital changed year-over-year?
Personalis, Inc.'s return on invested capital decreased by 15.1% year-over-year, from -44.7% to -51.5%.
What is the long-term trend for Personalis, Inc.'s return on invested capital?
Over 5 years (2020 to 2025), Personalis, Inc.'s return on invested capital has grown at a 3.7% compound annual growth rate (CAGR), from -44.1% to -52.9%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.