What is Protagonist Therapeutics's net debt / EBITDA?

Protagonist Therapeutics (PTGX) reported net debt / EBITDA of -5.1× in Q3 2025.

What does net debt / EBITDA mean?

Net debt (total debt minus cash) divided by trailing-twelve-month EBITDA. Expresses leverage in years — roughly how long it would take to repay net debt out of operating cash earnings.

Protagonist Therapeutics PTGX Net debt / EBITDA

Net debt / EBITDA at other companies

Bristol-Myers SquibbBMY

2.7×-0.1×

Eli LillyLLY

1.1×-1.1×

AmgenAMGN

3.7×-0.7×

IncyteINCY

-2×-0.8×

AbbVieABBV

2.5×—

Regeneron PharmaceuticalsREGN

-0.1×0.0×

Other financials

Income statement

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Revenue$56.4M+99.0%

Operating income-$3.6M+81.1%

Net income$3.8M+132%

EPS (diluted)$0.05+126%

Balance sheet

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Cash & equivalents$193.7M+38.7%

Total debt$9.8M-13.9%

Total equity$655.5M-4.9%

Total assets$697.5M-6.0%

Cash flow

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Operating cash flow-$48.9M-139%

CapEx$215.0K-60.6%

Free cash flow-$49.2M-139%

Valuation

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Market cap$7.26B+127%

Enterprise value$7.07B+130%

P/S98×+82.6×

Profitability

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Operating margin-192.4%-205pp

Net margin-154.9%-182pp

FCF margin-12,264.3%-12,527pp

Returns & leverage

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Return on equity-17.1%-26.1pp

Debt / equity0×0.0×

Current ratio17.8×+0.5×

Where this comes from

Calculated from Protagonist Therapeutics’s reported figures.

net debt/ebitda=-5.1×

Based on the most recent quarter.

The official record: Protagonist Therapeutics’s 10-Q, filed November 6, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Protagonist Therapeutics's net debt / EBITDA?: Protagonist Therapeutics (PTGX) reported net debt / EBITDA of -5.1× in Q3 2025.
What does net debt / EBITDA mean?: Net debt (total debt minus cash) divided by trailing-twelve-month EBITDA. Expresses leverage in years — roughly how long it would take to repay net debt out of operating cash earnings.