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Protagonist Therapeutics PTGX Return on invested capital

Return on invested capital at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
13%+4.2pp
Eli Lilly logo
Eli LillyLLY
42%+16.6pp
Amgen logo
AmgenAMGN
14.1%+4.0pp
Incyte logo
IncyteINCY
65.6%+61.0pp
AbbVie logo
AbbVieABBV
17.1%
Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
10.3%-2.0pp

Other financials

Income statement

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Revenue$56.4M+99.0%
Operating income-$3.6M+81.1%
Net income$3.8M+132%
EPS (diluted)$0.05+126%

Balance sheet

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Cash & equivalents$193.7M+38.7%
Total debt$9.8M-13.9%
Total equity$655.5M-4.9%
Total assets$697.5M-6.0%

Cash flow

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Operating cash flow-$48.9M-139%
CapEx$215.0K-60.6%
Free cash flow-$49.2M-139%

Valuation

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Market cap$7.26B+127%
Enterprise value$7.07B+130%
P/S98×+82.6×

Profitability

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Operating margin-192.4%-205pp
Net margin-154.9%-182pp
FCF margin-12,264.3%-12,527pp

Returns & leverage

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Return on equity-17.1%-26.1pp
Debt / equity0.0×
Current ratio17.8×+0.5×

Where this comes from

Calculated from Protagonist Therapeutics’s reported figures.

Based on trailing twelve months.

The official record: Protagonist Therapeutics’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Protagonist Therapeutics's return on invested capital?
Protagonist Therapeutics (PTGX) reported return on invested capital of -27.6% in Q1 2026.
How has Protagonist Therapeutics's return on invested capital changed year-over-year?
Protagonist Therapeutics's return on invested capital decreased by 588.8% year-over-year, from 5.6% to -27.6%.
What is the long-term trend for Protagonist Therapeutics's return on invested capital?
Over 4 years (2020 to 2025), Protagonist Therapeutics's return on invested capital has grown at a -14.9% compound annual growth rate (CAGR), from -55.6% to -29.1%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.