What is Simulations Plus's operating margin?

Simulations Plus (SLP) reported operating margin of -84.3% in Q4 2025.

What is the long-term trend for Simulations Plus's operating margin?

Over 4 years (2020 to 2025), Simulations Plus's operating margin has grown at a 34.1% compound annual growth rate (CAGR), from 27.9% to -90.2%.

What does operating margin mean?

Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.

Simulations Plus SLP Operating margin

Operating margin at other companies

SchrodingerSDGR

-64.7%-12.0pp

Certara, Inc.CERT

2.2%—

Charles River LaboratoriesCRL

13%-2.4pp

Personalis, Inc.PSNL

-158.9%-5,457pp

NeoGenomicsNEO

-14.2%+1.1pp

Opko HealthOPK

-17.4%-5.6pp

Other financials

Income statement

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Revenue$24.3M+8.3%

Gross profit$16.1M+23.0%

Operating income$5.6M+108%

Net income$4.5M+47.5%

EPS (diluted)$0.22+46.7%

Balance sheet

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Cash & equivalents$25.7M+134%

Total debt$508.0K-36.2%

Total equity$133.8M-29.4%

Total assets$146.5M-27.3%

Cash flow

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Operating cash flow$6.4M+13.1%

CapEx$46.0K-30.3%

Free cash flow$6.4M+13.6%

Valuation

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Market cap$366.73M+5.2%

Enterprise value$341.51M+6.0%

P/S4.6×+0.2×

Profitability

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Gross margin62%+6.7pp

Net margin-78%-87.2pp

FCF margin29.5%+14.9pp

Returns & leverage

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Return on equity-38.8%-42.8pp

Debt / equity0×0.0×

Current ratio5.5×+1.1×

Where this comes from

Calculated from Simulations Plus’s reported figures.

operating income/total revenue=-84.3%

Based on trailing twelve months.

The official record: Simulations Plus’s 10-Q, filed April 10, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Simulations Plus's operating margin?: Simulations Plus (SLP) reported operating margin of -84.3% in Q4 2025.
What is the long-term trend for Simulations Plus's operating margin?: Over 4 years (2020 to 2025), Simulations Plus's operating margin has grown at a 34.1% compound annual growth rate (CAGR), from 27.9% to -90.2%.
What does operating margin mean?: Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.