What is Xenon Pharmaceuticals's free cash flow margin?

Xenon Pharmaceuticals (XENE) reported free cash flow margin of -3,732.2% in Q4 2025.

What is the long-term trend for Xenon Pharmaceuticals's free cash flow margin?

Over 3 years (2020 to 2025), Xenon Pharmaceuticals's free cash flow margin has grown at a 187.0% compound annual growth rate (CAGR), from -157.8% to -3,732.2%.

What does free cash flow margin mean?

Free cash flow (operating cash flow minus capital expenditures) as a percentage of revenue, trailing twelve months. Measures how efficiently revenue converts into discretionary cash.

Xenon Pharmaceuticals XENE Free cash flow margin

Free cash flow margin at other companies

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16.4%+8.7pp

Johnson & JohnsonJNJ

18.5%-4.3pp

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28.6%-8.6pp

Axsome TherapeuticsAXSM

-10.2%-3.9pp

Praxis Precision Medicines, Inc.PRAX

-3,067.4%-1,030pp

Neurocrine BiosciencesNBIX

26.8%+6.4pp

Other financials

Income statement

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Revenue--100%

Operating income-$112.3M-54.4%

Net income-$102.3M-57.3%

EPS (diluted)-$1.17-41.0%

Balance sheet

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Cash & equivalents$545.9M+368%

Total debt$7.5M-13.6%

Total equity$1.3B+90.0%

Total assets$1.4B+86.6%

Cash flow

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Operating cash flow-$88.9M-44.2%

CapEx$133.0K+209%

Free cash flow-$89.0M-44.3%

Valuation

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Market cap$5.11B+116%

Enterprise value$4.58B+104%

Profitability

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Operating margin-4,974.3%—

Net margin-4,612.1%—

Returns & leverage

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Return on equity-37.5%+8.7pp

Debt / equity0×0.0×

Current ratio27.8×+10.1×

Where this comes from

Calculated from Xenon Pharmaceuticals’s reported figures.

free cash flow/total revenue=-3,732.2%

Based on trailing twelve months.

The official record: Xenon Pharmaceuticals’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Xenon Pharmaceuticals's free cash flow margin?: Xenon Pharmaceuticals (XENE) reported free cash flow margin of -3,732.2% in Q4 2025.
What is the long-term trend for Xenon Pharmaceuticals's free cash flow margin?: Over 3 years (2020 to 2025), Xenon Pharmaceuticals's free cash flow margin has grown at a 187.0% compound annual growth rate (CAGR), from -157.8% to -3,732.2%.
What does free cash flow margin mean?: Free cash flow (operating cash flow minus capital expenditures) as a percentage of revenue, trailing twelve months. Measures how efficiently revenue converts into discretionary cash.