What is Xenon Pharmaceuticals's net margin?

Xenon Pharmaceuticals (XENE) reported net margin of -4,612.1% in Q4 2025.

What is the long-term trend for Xenon Pharmaceuticals's net margin?

Over 3 years (2020 to 2025), Xenon Pharmaceuticals's net margin has grown at a 271.9% compound annual growth rate (CAGR), from -89.7% to -4,612.1%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Xenon Pharmaceuticals XENE Net margin

Net margin at other companies

Eli LillyLLY

35%+12.3pp

Johnson & JohnsonJNJ

21.8%-2.6pp

Jazz PharmaceuticalsJAZZ

-8.9%-20.5pp

Axsome TherapeuticsAXSM

-26.6%-9.8pp

Praxis Precision Medicines, Inc.PRAX

-3,658.5%-1,388pp

Neurocrine BiosciencesNBIX

21.6%+8.9pp

Other financials

Income statement

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Revenue--100%

Operating income-$112.3M-54.4%

Net income-$102.3M-57.3%

EPS (diluted)-$1.17-41.0%

Balance sheet

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Cash & equivalents$545.9M+368%

Total debt$7.5M-13.6%

Total equity$1.3B+90.0%

Total assets$1.4B+86.6%

Cash flow

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Operating cash flow-$88.9M-44.2%

CapEx$133.0K+209%

Free cash flow-$89.0M-44.3%

Valuation

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Market cap$5.11B+116%

Enterprise value$4.58B+104%

Profitability

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Operating margin-4,974.3%—

FCF margin-3,732.2%—

Returns & leverage

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Return on equity-37.5%+8.7pp

Debt / equity0×0.0×

Current ratio27.8×+10.1×

Where this comes from

Calculated from Xenon Pharmaceuticals’s reported figures.

net income/total revenue=-4,612.1%

Based on trailing twelve months.

The official record: Xenon Pharmaceuticals’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Xenon Pharmaceuticals's net margin?: Xenon Pharmaceuticals (XENE) reported net margin of -4,612.1% in Q4 2025.
What is the long-term trend for Xenon Pharmaceuticals's net margin?: Over 3 years (2020 to 2025), Xenon Pharmaceuticals's net margin has grown at a 271.9% compound annual growth rate (CAGR), from -89.7% to -4,612.1%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.