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Xencor XNCR Operating margin

Operating margin at other companies

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AmgenAMGN
30%+6.5pp
Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
24.7%-2.3pp
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Janux TherapeuticsJANX
-598.1%-296pp
AbCellera Biologics Inc. logo
AbCellera Biologics Inc.ABCL
-340.3%-127pp
AnaptysBio, Inc. logo
AnaptysBio, Inc.ANAB
17.6%+9.6pp
Xenon Pharmaceuticals logo
Xenon PharmaceuticalsXENE
-4,974.3%

Other financials

Income statement

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Revenue$51.2M+17.5%
Operating income-$37.1M-11.7%
Net income-$21.7M+29.5%
EPS (diluted)-$0.29+29.3%

Balance sheet

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Cash & equivalents$44.7M+0.5%
Total debt$170.1M-20.1%
Total equity$503.2M-18.9%
Total assets$725.0M-17.6%

Cash flow

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Operating cash flow-$55.7M-53.0%
CapEx$538.0K+40.5%
Free cash flow-$56.2M-52.9%

Valuation

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Market cap$1.55B+210%
Enterprise value$1.67B+150%
P/S14.7×+11.3×

Profitability

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Net margin-155.6%+78.8pp
FCF margin-198.4%-1,485pp

Returns & leverage

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Return on equity-29.1%+0.2pp
Debt / equity0.3×0.0×
Current ratio6.4×+1.1×

Where this comes from

Calculated from Xencor’s reported figures.

Based on trailing twelve months.

The source filing: Xencor’s 10-Q, filed August 5, 2026. Open the filing →

Filed
Aug 5, 2026, 4:02 PM EDT
Fiscal quarter
Q4 FY2028
Calendar quarter
Q4 2028
Accession
0001326732-26-000056

FAQ

What is Xencor's operating margin?
Xencor (XNCR) reported operating margin of -205.8% in Q2 2026.
How has Xencor's operating margin changed year-over-year?
Xencor's operating margin decreased by 109.0% year-over-year, from -98.5% to -205.8%.
What is the long-term trend for Xencor's operating margin?
Over 5 years (2020 to 2025), Xencor's operating margin has grown at a 17.7% compound annual growth rate (CAGR), from -62.6% to -141.4%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.

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