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Xencor XNCR Operating margin

Operating margin at other companies

Amgen logo
AmgenAMGN
28.4%+6.6pp
Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
24.3%-2.9pp
Janux Therapeutics logo
Janux TherapeuticsJANX
-1,143.1%-65.1pp
AbCellera Biologics Inc. logo
AbCellera Biologics Inc.ABCL
-267.6%-120pp
AnaptysBio, Inc. logo
AnaptysBio, Inc.ANAB
17.6%+9.6pp
Xenon Pharmaceuticals logo
Xenon PharmaceuticalsXENE
-4,974.3%

Other financials

Income statement

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Revenue$4.5M-86.2%
Operating income-$77.9M-80.3%
Net income-$128.9M-166%
EPS (diluted)-$1.71-159%

Balance sheet

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Cash & equivalents$14.2M-64.3%
Total debt$175.2M-21.2%
Total equity$515.6M-19.4%
Total assets$736.8M-18.6%

Cash flow

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Operating cash flow-$67.6M-317%
CapEx$610.0K-57.8%
Free cash flow-$68.2M-286%

Valuation

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Market cap$1.07B+76.3%
Enterprise value$1.23B+55.9%
P/S11×+6.2×

Profitability

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Net margin-177.1%+16.5pp
FCF margin-194%+166pp

Returns & leverage

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Return on equity-29.8%-2.7pp
Debt / equity0.3×0.0×
Current ratio6.6×+0.7×

Where this comes from

Calculated from Xencor’s reported figures.

Based on trailing twelve months.

The official record: Xencor’s 10-Q, filed May 6, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Xencor's operating margin?
Xencor (XNCR) reported operating margin of -217.9% in Q1 2026.
How has Xencor's operating margin changed year-over-year?
Xencor's operating margin decreased by 66.1% year-over-year, from -131.2% to -217.9%.
What is the long-term trend for Xencor's operating margin?
Over 5 years (2020 to 2025), Xencor's operating margin has grown at a 17.7% compound annual growth rate (CAGR), from -62.6% to -141.4%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.