What is Xencor's net margin?

Xencor (XNCR) reported net margin of -177.1% in Q1 2026.

How has Xencor's net margin changed year-over-year?

Xencor's net margin decreased by 8.5% year-over-year, from -163.2% to -177.1%.

What is the long-term trend for Xencor's net margin?

Over 5 years (2020 to 2025), Xencor's net margin has grown at a 5.3% compound annual growth rate (CAGR), from -56.5% to -73.2%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Xencor XNCR Net margin

Net margin at other companies

AmgenAMGN

21%+3.6pp

Regeneron PharmaceuticalsREGN

29.6%-2.3pp

Janux TherapeuticsJANX

-833.6%+0.9pp

AbCellera Biologics Inc.ABCL

-181.7%-77.9pp

AnaptysBio, Inc.ANAB

-49.9%-22.6pp

Xenon PharmaceuticalsXENE

-4,612.1%—

Other financials

Income statement

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Revenue$4.5M-86.2%

Operating income-$77.9M-80.3%

Net income-$128.9M-166%

EPS (diluted)-$1.71-159%

Balance sheet

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Cash & equivalents$14.2M-64.3%

Total debt$175.2M-21.2%

Total equity$515.6M-19.4%

Total assets$736.8M-18.6%

Cash flow

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Operating cash flow-$67.6M-317%

CapEx$610.0K-57.8%

Free cash flow-$68.2M-286%

Valuation

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Market cap$1.07B+76.3%

Enterprise value$1.23B+55.9%

P/S11×+6.2×

Profitability

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Operating margin-217.9%+425pp

FCF margin-194%+166pp

Returns & leverage

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Return on equity-29.8%-2.7pp

Debt / equity0.3×0.0×

Current ratio6.6×+0.7×

Where this comes from

Calculated from Xencor’s reported figures.

net income/total revenue=-177.1%

Based on trailing twelve months.

The official record: Xencor’s 10-Q, filed May 6, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Xencor's net margin?: Xencor (XNCR) reported net margin of -177.1% in Q1 2026.
How has Xencor's net margin changed year-over-year?: Xencor's net margin decreased by 8.5% year-over-year, from -163.2% to -177.1%.
What is the long-term trend for Xencor's net margin?: Over 5 years (2020 to 2025), Xencor's net margin has grown at a 5.3% compound annual growth rate (CAGR), from -56.5% to -73.2%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.