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Zymeworks ZYME Operating margin

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Other financials

Income statement

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Revenue$2.4M-91.1%
Operating income-$47.1M-84.0%
Net income-$44.2M-95.1%
EPS (diluted)-$0.59-96.7%

Balance sheet

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Cash & equivalents$244.3M+221%
Total debt$17.0M-7.7%
Total equity$163.6M-49.7%
Total assets$478.2M+12.4%

Cash flow

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Operating cash flow-$45.7M-1,242%
CapEx$216.0K+1,250%
Free cash flow-$45.9M-1,242%

Valuation

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Market cap$1.76B+125%
Enterprise value$1.53B+112%
P/S21.6×+13.2×

Profitability

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Net margin-126.3%+5.0pp
FCF margin-94.8%+15.5pp

Returns & leverage

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Return on equity-42%+29.2pp
Debt / equity0.1×0.0×
Current ratio10.8×+6.1×

Where this comes from

Calculated from Zymeworks’s reported figures.

Based on trailing twelve months.

The official record: Zymeworks’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Zymeworks's operating margin?
Zymeworks (ZYME) reported operating margin of -140.4% in Q1 2026.
How has Zymeworks's operating margin changed year-over-year?
Zymeworks's operating margin decreased by 4.9% year-over-year, from -133.8% to -140.4%.
What is the long-term trend for Zymeworks's operating margin?
Over 4 years (2020 to 2025), Zymeworks's operating margin has grown at a -34.7% compound annual growth rate (CAGR), from -481.3% to -87.3%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.