Total Cost of Revenue
Vertex Pharmaceuticals Total Cost of Revenue decreased by 15.7% to $392.80M in Q1 2026 compared to the prior quarter. Year-over-year, this metric grew by 8.2%, from $363.00M to $392.80M. Over 4 years (FY 2021 to FY 2025), Total Cost of Revenue shows an upward trend with a 16.2% CAGR. This increase may warrant attention — for this metric, lower values are generally preferred.
Analysis
How to read this metric
An increase relative to revenue suggests rising production costs or margin compression, while a decrease suggests improved operational efficiency.
Detailed definition
Total cost of revenue includes the direct costs attributable to the production of goods or the delivery of services sold...
Peer comparison
Varies by industry; for medical device manufacturers, this includes significant manufacturing and supply chain costs.
total_cost_of_revenueHistorical Data
| Q2 '21 | Q3 '21 | Q4 '21 | Q1 '22 | Q2 '22 | Q3 '22 | Q4 '22 | Q1 '23 | Q2 '23 | Q3 '23 | Q4 '23 | Q1 '24 | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Value | $228.00M | $236.50M | $247.40M | $245.80M | $261.80M | $289.40M | $283.30M | $266.90M | $308.60M | $318.70M | $368.00M | $342.60M | $371.90M | $392.60M | $423.40M | $363.00M | $407.50M | $414.80M | $466.00M | $392.80M |
| QoQ Change | — | +3.7% | +4.6% | -0.6% | +6.5% | +10.5% | -2.1% | -5.8% | +15.6% | +3.3% | +15.5% | -6.9% | +8.6% | +5.6% | +7.8% | -14.3% | +12.3% | +1.8% | +12.3% | -15.7% |
| YoY Change | — | — | — | — | +14.8% | +22.4% | +14.5% | +8.6% | +17.9% | +10.1% | +29.9% | +28.4% | +20.5% | +23.2% | +15.1% | +6.0% | +9.6% | +5.7% | +10.1% | +8.2% |
Product Breakdown
| Segment | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|
| Product revenues, net | $130.60M | $140.50M | $139.60M | $190.80M | $160.20M |
| Royalty | $232.40M | — | — | — | — |
| Total | $363.00M | $407.50M | $414.80M | $466.00M | $392.80M |
Total Cost of Revenue at Other Companies
Frequently Asked Questions
- What is Vertex Pharmaceuticals's total cost of revenue?
- Vertex Pharmaceuticals (VRTX) reported total cost of revenue of $392.80M in Q1 2026.
- How has Vertex Pharmaceuticals's total cost of revenue changed year-over-year?
- Vertex Pharmaceuticals's total cost of revenue increased by 8.2% year-over-year, from $363.00M to $392.80M.
- What is the long-term trend for Vertex Pharmaceuticals's total cost of revenue?
- Over 4 years (2021 to 2025), Vertex Pharmaceuticals's total cost of revenue has grown at a 16.2% compound annual growth rate (CAGR), from $904.20M to $1.65B.
- What does total cost of revenue mean?
- The direct costs incurred to produce the goods or services that a company sold during a specific period.