What is Agios Pharmaceuticals's gross margin?

Agios Pharmaceuticals (AGIO) reported gross margin of 90% in Q1 2026.

How has Agios Pharmaceuticals's gross margin changed year-over-year?

Agios Pharmaceuticals's gross margin increased by 2.9% year-over-year, from 87.5% to 90%.

What does gross margin mean?

Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.

Agios Pharmaceuticals AGIO Gross margin

Gross margin at other companies

Bristol-Myers SquibbBMY

70.5%0.0pp

PfizerPFE

73.5%+1.2pp

Vertex PharmaceuticalsVRTX

86.2%+0.2pp

IncyteINCY

92.5%-0.2pp

BioMarin PharmaceuticalsBMRN

76.5%-2.9pp

BioCryst PharmaceuticalsBCRX

97.8%+0.8pp

Other financials

Income statement

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Revenue$20.7M+138%

Gross profit$19.4M+154%

Operating income-$110.0M-3.2%

Net income-$99.1M-11.0%

EPS (diluted)-$1.69-9.0%

Balance sheet

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Cash & equivalents$113.6M+43.9%

Total debt$35.7M-32.5%

Total equity$1.1B-24.4%

Total assets$1.2B-23.8%

Cash flow

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Operating cash flow-$118.9M-6.7%

CapEx$769.0K+0.4%

Free cash flow-$119.7M-6.6%

Valuation

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Market cap$2.12B+18.1%

Enterprise value$2.04B+15.2%

P/S32.1×-16.4×

Profitability

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Operating margin-720%-204pp

Net margin-639.8%—

FCF margin-582.5%-185pp

Returns & leverage

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Return on equity-32.8%—

Debt / equity0×0.0×

Current ratio14.2×-4.3×

Where this comes from

Calculated from Agios Pharmaceuticals’s reported figures.

gross profit/total revenue=90%

Based on trailing twelve months.

The official record: Agios Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Agios Pharmaceuticals's gross margin?: Agios Pharmaceuticals (AGIO) reported gross margin of 90% in Q1 2026.
How has Agios Pharmaceuticals's gross margin changed year-over-year?: Agios Pharmaceuticals's gross margin increased by 2.9% year-over-year, from 87.5% to 90%.
What does gross margin mean?: Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.