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Operating margin at other companies

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38.3%
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30%+26.1pp
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-2,890.9%
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-83.8%-3.0pp
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-43.1%-49.7pp

Other financials

Income statement

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Revenue$20.7M+138%
Gross profit$19.4M+154%
Operating income-$110.0M-3.2%
Net income-$99.1M-11.0%
EPS (diluted)-$1.69-9.0%

Balance sheet

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Cash & equivalents$113.6M+43.9%
Total debt$35.7M-32.5%
Total equity$1.1B-24.4%
Total assets$1.2B-23.8%

Cash flow

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Operating cash flow-$118.9M-6.7%
CapEx$769.0K+0.4%
Free cash flow-$119.7M-6.6%

Valuation

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Market cap$2.12B+18.1%
Enterprise value$2.04B+15.2%
P/S32.1×-16.4×

Profitability

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Gross margin90%+2.5pp
Net margin-639.8%
FCF margin-582.5%-185pp

Returns & leverage

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Return on equity-32.8%
Debt / equity0.0×
Current ratio14.2×-4.3×

Where this comes from

Calculated from Agios Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The official record: Agios Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Agios Pharmaceuticals's operating margin?
Agios Pharmaceuticals (AGIO) reported operating margin of -720% in Q1 2026.
How has Agios Pharmaceuticals's operating margin changed year-over-year?
Agios Pharmaceuticals's operating margin increased by 39.4% year-over-year, from -1,188.9% to -720%.
What is the long-term trend for Agios Pharmaceuticals's operating margin?
Over 4 years (2020 to 2025), Agios Pharmaceuticals's operating margin has grown at a 50.8% compound annual growth rate (CAGR), from -168.8% to -873.9%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.