What is Agios Pharmaceuticals's net margin?

Agios Pharmaceuticals (AGIO) reported net margin of -639.8% in Q1 2026.

What is the long-term trend for Agios Pharmaceuticals's net margin?

Over 2 years (2020 to 2025), Agios Pharmaceuticals's net margin has grown at a 117.8% compound annual growth rate (CAGR), from -161.1% to -764%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Agios Pharmaceuticals AGIO Net margin

Net margin at other companies

Bristol-Myers SquibbBMY

15%+3.8pp

PfizerPFE

15.7%—

Vertex PharmaceuticalsVRTX

35.5%—

IncyteINCY

26.7%+26.2pp

BioMarin PharmaceuticalsBMRN

16.8%+5.1pp

PrecigenPGEN

-3,656%—

Other financials

Income statement

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Revenue$20.7M+138%

Gross profit$19.4M+154%

Operating income-$110.0M-3.2%

Net income-$99.1M-11.0%

EPS (diluted)-$1.69-9.0%

Balance sheet

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Cash & equivalents$113.6M+43.9%

Total debt$35.7M-32.5%

Total equity$1.1B-24.4%

Total assets$1.2B-23.8%

Cash flow

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Operating cash flow-$118.9M-6.7%

CapEx$769.0K+0.4%

Free cash flow-$119.7M-6.6%

Valuation

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Market cap$2.12B+18.1%

Enterprise value$2.04B+15.2%

P/S32.1×-16.4×

Profitability

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Gross margin90%+2.5pp

Operating margin-720%-204pp

FCF margin-582.5%-185pp

Returns & leverage

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Return on equity-32.8%—

Debt / equity0×0.0×

Current ratio14.2×-4.3×

Where this comes from

Calculated from Agios Pharmaceuticals’s reported figures.

net income/total revenue=-639.8%

Based on trailing twelve months.

The official record: Agios Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Agios Pharmaceuticals's net margin?: Agios Pharmaceuticals (AGIO) reported net margin of -639.8% in Q1 2026.
What is the long-term trend for Agios Pharmaceuticals's net margin?: Over 2 years (2020 to 2025), Agios Pharmaceuticals's net margin has grown at a 117.8% compound annual growth rate (CAGR), from -161.1% to -764%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.