Discontinued — last reported Q4 '25

Enbrel® (etanercept) — Total revenues

Products & Services · Total revenues

Amgen Enbrel® (etanercept) — Total revenues remained flat by 0.0% to $556.50M in Q4 2025 compared to the prior quarter. Year-over-year, this metric declined by 32.9%, from $829.00M to $556.50M. Over 2 years (FY 2023 to FY 2025), Enbrel® (etanercept) — Total revenues shows a downward trend with a -22.4% CAGR. This decline may warrant attention — for this metric, higher values are generally preferred.

Analysis

StatementSegment
CategoryGrowth
SignalHigher is better
VolatilityModerate
First reportedQ3 2020
Last reportedQ4 2025
Rolls up toTotal Revenue

How to read this metric

An increase suggests strong market retention and effective lifecycle management, while a decrease indicates potential market share erosion due to patent expirations or the introduction of biosimilar competitors.

Detailed definition

This metric represents the total gross revenue generated from the sale of a specific flagship therapeutic product within...

Peer comparison

Comparable to revenue metrics for mature, branded pharmaceutical products or legacy blockbusters in the portfolios of large-cap biopharmaceutical peers.

Metric ID: amgn_segment_enbrel_total_revenues

Historical Data

16 periods
 Q2 '21Q3 '21Q1 '22Q2 '22Q1 '23Q2 '23Q3 '23Q4 '23Q1 '24Q2 '24Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25
Value$1.14B$1.29B$862.00M$1.05B$924.25M$924.25M$924.25M$924.25M$829.00M$829.00M$829.00M$829.00M$556.50M$556.50M$556.50M$556.50M
QoQ Change+12.7%-33.1%+21.9%-12.1%+0.0%+0.0%+0.0%-10.3%+0.0%+0.0%+0.0%-32.9%+0.0%+0.0%+0.0%
YoY Change-8.1%+7.2%-12.1%-10.3%-10.3%-10.3%-10.3%-32.9%-32.9%-32.9%-32.9%
Range$556.50M$1.29B
CAGR-17.5%
Avg YoY Growth-16.9%
Median YoY Growth-10.3%
Current Streak3 quarters growth

Frequently Asked Questions

What is Amgen's enbrel® (etanercept) — total revenues?
Amgen (AMGN) reported enbrel® (etanercept) — total revenues of $556.50M in Q4 2025.
How has Amgen's enbrel® (etanercept) — total revenues changed year-over-year?
Amgen's enbrel® (etanercept) — total revenues decreased by 32.9% year-over-year, from $829.00M to $556.50M.
What is the long-term trend for Amgen's enbrel® (etanercept) — total revenues?
Over 2 years (2023 to 2025), Amgen's enbrel® (etanercept) — total revenues has grown at a -22.4% compound annual growth rate (CAGR), from $3.70B to $2.23B.
What does enbrel® (etanercept) — total revenues mean?
The total sales revenue generated by the company's specific flagship therapeutic product for inflammatory diseases.

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