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Amylyx Pharmaceuticals, Inc. AMLX Return on invested capital

Return on invested capital at other companies

MBX Biosciences, Inc. logo
MBX Biosciences, Inc.MBX
-33%
Viking Therapeutics logo
Viking TherapeuticsVKTX
-59.2%-292pp
Beam Therapeutics logo
Beam TherapeuticsBEAM
-39.4%-8.8pp
Crinetics Pharmaceuticals logo
Crinetics PharmaceuticalsCRNX
-45.1%+1.9pp
Agios Pharmaceuticals logo
Agios PharmaceuticalsAGIO
-38.5%-2.4pp
Rhythm Pharmaceuticals, Inc. logo
Rhythm Pharmaceuticals, Inc.RYTM
-197.9%-87.7pp

Other financials

Income statement

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Revenue-
Gross profit-
Operating income-$43.8M-15.8%
Net income-$41.3M-15.0%
EPS (diluted)-$0.37+11.9%

Balance sheet

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Cash & equivalents$229.1M+283%
Total debt$5.6M+307%
Total equity$273.2M+35.6%
Total assets$293.6M+33.7%

Cash flow

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Operating cash flow-$36.9M+7.4%
CapEx$86.0K+330%
Free cash flow-$28.0M+52.6%

Valuation

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Market cap$1.82B+390%
Enterprise value$1.6B+414%

Profitability

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Gross margin100%+6.9pp
Operating margin-47,349.8%-47,409pp
Net margin-45,096.2%-45,152pp
FCF margin-39,826.7%-39,847pp

Returns & leverage

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Return on equity-63.3%-12.2pp
Debt / equity0.0×
Current ratio17.9×+5.8×

Where this comes from

Calculated from Amylyx Pharmaceuticals, Inc.’s reported figures.

Based on trailing twelve months.

The official record: Amylyx Pharmaceuticals, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Amylyx Pharmaceuticals, Inc.'s return on invested capital?
Amylyx Pharmaceuticals, Inc. (AMLX) reported return on invested capital of -165.3% in Q1 2026.
How has Amylyx Pharmaceuticals, Inc.'s return on invested capital changed year-over-year?
Amylyx Pharmaceuticals, Inc.'s return on invested capital decreased by 7.8% year-over-year, from -153.3% to -165.3%.
What is the long-term trend for Amylyx Pharmaceuticals, Inc.'s return on invested capital?
Over 2 years (2023 to 2025), Amylyx Pharmaceuticals, Inc.'s return on invested capital has grown at a 271.7% compound annual growth rate (CAGR), from 12.8% to -176.3%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.