What are CareDx's profit margins?

CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.

Where do CareDx's ratios come from?

Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

CareDx CDNA Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Operating margin	-3.9%+4.2pp	-8.1%-24.8pp	16.7%+3.1pp	13.5%-0.9pp	14.4%+2.2pp
Net margin	-2%+3.6pp	-5.6%-25.3pp	19.7%+2.6pp	17.1%-0.9pp	17.9%+2.2pp
EBITDA margin	-0.2%+3.9pp	-4.2%-24.9pp	20.7%+3.0pp	17.7%-0.8pp	18.5%+2.0pp
Returns
Return on equity	-2.4%+3.9pp	-6.3%-30.4pp	24.1%+4.5pp	19.6%+0.1pp	19.5%+3.1pp
Return on assets	-1.8%+2.9pp	-4.7%-20.2pp	15.5%+2.7pp	12.8%-0.4pp	13.2%+2.2pp
Return on invested capital	-5.6%+5.5pp	-11.1%-37.3pp	26.2%+7.4pp	18.8%-0.4pp	19.2%+3.2pp
Efficiency
Asset turnover	0.9×+0.1×	0.8×+0.1×	0.8×0.0×	0.7×0.0×	0.7×0.0×
Liquidity
Current ratio	3.4×+0.5×	2.9×-0.2×	3×-0.3×	3.3×-0.8×	4.1×+0.2×
Quick ratio	3.1×+0.5×	2.6×-0.2×	2.7×-0.3×	3×-0.8×	3.8×+0.1×
Cash ratio	1×+0.3×	0.7×-0.2×	0.9×+0.2×	0.7×-0.3×	1×-0.2×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Debt-to-assets	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Interest coverage	-2×+1.4×	-3.4×-9.2×	5.8×+1.7×	4.1×-0.2×	4.3×+0.8×
Per Share
Book value per share	$5.90+3.8%	$5.69-1.8%	$5.79-4.0%	$6.03-12.2%	$6.86+2.7%
Valuation
Market capitalization	$1.4B+35.7%	$968.99M+25.2%	$773.92M-26.4%	$1.05B+6.9%	$983.81M-14.3%
Enterprise value	$1.35B+38.3%	$929.2M+31.0%	$709.58M-29.9%	$1.01B+9.4%	$924.79M-12.9%
Price / sales	3.4×+0.4×	2.6×+0.4×	2.2×-0.9×	3.1×+0.2×	2.8×-0.6×
Price / book	4.6×+1.8×	3.2×+0.7×	2.5×-0.7×	3.2×+0.6×	2.6×-0.4×
EV / sales	3.4×+0.5×	2.4×+0.5×	2×-1.0×	3×+0.3×	2.7×-0.5×
Earnings yield	-0.6%-6.4pp	-2.2%-11.3pp	9.1%+3.6pp	5.5%-0.8pp	6.3%+1.7pp

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Questions, answered.

What are CareDx's profit margins?: CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.
Where do CareDx's ratios come from?: Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.