What are Crinetics Pharmaceuticals's profit margins?

Gross margin is 150.0% and operating margin is -3020.3%, with a -2747.2% net margin.

Where does Crinetics Pharmaceuticals's income statement data come from?

Every line is extracted from Crinetics Pharmaceuticals's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.

Crinetics Pharmaceuticals CRNX Income Statement

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Total revenue	$18.07M+135%	$7.7M+401%	$1.54M+10.3%	$1.39M+83.2%	$760K-26.9%
Total cost of revenue	——	——	——	——	$0—
Gross profit	——	——	——	——	$1.14M+9.7%
Research and development	$355.9M+7.2%	$332.06M+5.9%	$313.57M+10.0%	$285.01M+8.3%	$263.06M+9.5%
Selling, general and administrative	——	$191.33M+13.6%	$168.43M+15.7%	$145.53M+18.7%	$122.64M+23.0%
General and administrative	——	——	$165.81M+18.9%	$139.44M+21.8%	$114.44M+14.7%
Total costs & expenses	——	——	——	——	$366.69M+7.9%
Operating income	-$545.74M-5.6%	-$516.77M-8.1%	-$477.85M-13.0%	-$423.06M-12.3%	-$376.73M-11.2%
Operating margin	-3,020.3%+3,694pp	-6,714.8%+24,415pp	-31,130.2%-738pp	-30,392.2%+19,178pp	-49,569.7%-16,956pp
Interest income	$49.82M-4.2%	$51.99M-5.8%	$55.2M+2.9%	$53.66M+9.6%	$48.95M+18.1%
Other income (expense), net	$49.53M-4.1%	$51.63M-5.7%	$54.75M+2.9%	$53.23M+9.8%	$48.48M+18.5%
Income tax expense	——	$180K+33.3%	$135K+50.0%	$90K+100%	$45K—
Net income	-$496.39M-6.7%	-$465.32M-10.0%	-$423.1M-14.4%	-$369.83M-12.7%	-$328.25M-10.0%
Net margin	-2,747.2%+3,299pp	-6,046.2%+21,517pp	-27,563.3%-995pp	-26,568.5%+16,623pp	-43,191.1%-14,470pp
Diluted earnings per share	-$5.13-3.8%	-$4.94-9.3%	-$4.52-10.2%	-$4.10-7.6%	-$3.81-3.0%
Basic earnings per share	-$5.13-3.8%	-$4.94-9.3%	-$4.52-10.2%	-$4.10-7.6%	-$3.81-3.0%
Weighted-average shares, diluted	386.2M+2.9%	375.2M+3.7%	361.9M+4.1%	347.8M+4.4%	333M+6.7%
Weighted-average shares, basic	386.2M+2.9%	375.2M+3.7%	361.9M+4.1%	347.8M+4.4%	333M+6.7%
Comprehensive Income (Loss), Net of Tax, Attributable to Parent	-$499.64M-7.6%	-$464.42M-9.8%	-$422.94M-14.9%	-$368.02M-12.8%	-$326.4M-9.4%
Income (Loss) From Continuing Operations Before Equity Method Investments, Net Of Tax	——	-$465.32M-9.9%	-$423.47M-11.0%	-$381.63M-12.3%	-$339.78M-14.0%
Other Comprehensive Income Foreign Currency Transaction And Translation Gain Loss Arising During Period Net Of Tax	-$150K+12.8%	-$172K-251%	-$49K-75.0%	-$28K-567%	$6K—
Net unrealized gains (losses) on securities still held	——	——	$205K-88.9%	$1.84M-0.4%	$1.85M+13,286%
Other income, net (Note 6)	-$305K+19.1%	-$377K+19.8%	-$470K-2.6%	-$458K—	——
Revenue From Contract With Customer Excluding Assessed Tax	$18.07M+135%	$7.7M+401%	$1.54M+10.3%	$1.39M+83.2%	$760K-26.9%
EBIT	-$545.74M-5.6%	-$516.77M-8.1%	-$477.85M-13.0%	-$423.06M-12.3%	-$376.73M-11.2%
EBITDA	-$541.62M-5.6%	-$512.88M-8.2%	-$474.16M-13.0%	-$419.62M-12.3%	-$373.49M-11.1%
EBITDA	-$541.62M-5.6%	-$512.88M-8.2%	-$474.16M-13.0%	-$419.62M-12.3%	-$373.49M-11.1%
EBITDA margin	-2,997.5%+3,667pp	-6,664.2%+24,226pp	-30,890.2%-745pp	-30,144.9%+18,999pp	-49,143.9%-16,799pp
EBIT	-$545.74M-5.6%	-$516.77M-8.1%	-$477.85M-13.0%	-$423.06M-12.3%	-$376.73M-11.2%

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Questions, answered.

What are Crinetics Pharmaceuticals's profit margins?: Gross margin is 150.0% and operating margin is -3020.3%, with a -2747.2% net margin.
Where does Crinetics Pharmaceuticals's income statement data come from?: Every line is extracted from Crinetics Pharmaceuticals's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.