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Denali Therapeutics Inc. DNLI Business Segments — Personnel related research and development expenses

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Other financials

Income statement

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Revenue$3.6M
Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

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Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

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Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

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Market cap$3.92B+88.3%
Enterprise value$3.76B+89.0%
P/S1,089×+1,084×

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept dnli:PersonnelRelatedResearchAndDevelopmentExpense.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 4:08 PM EDT
Fiscal quarter
Q4 FY2026
Calendar quarter
Q4 2026
Accession
0001714899-26-000097
Line itemTherapeutics Segment / Three Months Ended June 30, 2026Therapeutics Segment / Three Months Ended June 30, 2025Therapeutics Segment / Six Months Ended June 30, 2026Therapeutics Segment / Six Months Ended June 30, 2025
Cost of goods sold9393
External research and development expenses - TV programs, including cost sharing40,41937,59478,88384,052
Other research and development expenses, including small molecule programs16,49424,84740,04854,347
Personnel related research and development expenses40,10640,25581,93480,524
Total research and development expenses97,019102,696200,865218,923
Personnel related selling, general and administrative expenses22,92120,11545,48538,853
Other selling, general and administrative expenses13,36212,15224,30922,767
Total selling, general and administrative expenses36,28332,26769,79461,620

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s business segments — personnel related research and development expenses?
Denali Therapeutics Inc. (DNLI) reported business segments — personnel related research and development expenses of $40.11M in Q2 2026.
How has Denali Therapeutics Inc.'s business segments — personnel related research and development expenses changed year-over-year?
Denali Therapeutics Inc.'s business segments — personnel related research and development expenses decreased by 0.4% year-over-year, from $40.26M to $40.11M.
What is the long-term trend for Denali Therapeutics Inc.'s business segments — personnel related research and development expenses?
Over 3 years (2022 to 2025), Denali Therapeutics Inc.'s business segments — personnel related research and development expenses has grown at a 5.3% compound annual growth rate (CAGR), from $144.02M to $168.22M.
What does business segments — personnel related research and development expenses mean?
Includes all compensation, benefits, and stock-based compensation for employees directly involved in research and development activities. This metric serves as a proxy for the company's investment in human capital and scientific talent. High levels of these expenses indicate a focus on building internal expertise to drive long-term therapeutic innovation.

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