Skip to content
Screener

Denali Therapeutics Inc. DNLI Business Segments — Research and Development Expense

Similar metrics at other companies

Wabtec logo
WABFreight Segment — Research and Development Expense
$55M+44.7%
Wabtec logo
WABTransit Segment — Research and Development Expense
$15M+25.0%
Brunswick logo
BCCorporate Segment — Research and Development Expense
$1.1M+10.0%
Keysight Technologies logo
KEYSTotal segments — Research and Development Expense
$303M+27.3%
Keysight Technologies logo
KEYSCSG — Research and Development Expense
$226M+29.1%
Keysight Technologies logo
KEYSEISG — Research and Development Expense
$77M+22.2%

Other financials

Income statement

See full
Revenue$3.6M
Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

See full
Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

See full
Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

See full
Market cap$3.92B+88.3%
Enterprise value$3.76B+89.0%
P/S1,089×+1,084×

Profitability

See full
Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

See full
Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:ResearchAndDevelopmentExpense.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 4:08 PM EDT
Fiscal quarter
Q4 FY2026
Calendar quarter
Q4 2026
Accession
0001714899-26-000097
Line itemTherapeutics Segment / Three Months Ended June 30, 2026Therapeutics Segment / Three Months Ended June 30, 2025Therapeutics Segment / Six Months Ended June 30, 2026Therapeutics Segment / Six Months Ended June 30, 2025
External research and development expenses - TV programs, including cost sharing40,41937,59478,88384,052
Other research and development expenses, including small molecule programs16,49424,84740,04854,347
Personnel related research and development expenses40,10640,25581,93480,524
Total research and development expenses97,019102,696200,865218,923
Personnel related selling, general and administrative expenses22,92120,11545,48538,853
Other selling, general and administrative expenses13,36212,15224,30922,767
Total selling, general and administrative expenses36,28332,26769,79461,620
Intangible asset amortization$750$750

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s business segments — research and development expense?
Denali Therapeutics Inc. (DNLI) reported business segments — research and development expense of $97.02M in Q2 2026.
How has Denali Therapeutics Inc.'s business segments — research and development expense changed year-over-year?
Denali Therapeutics Inc.'s business segments — research and development expense decreased by 5.5% year-over-year, from $102.7M to $97.02M.
What is the long-term trend for Denali Therapeutics Inc.'s business segments — research and development expense?
Over 3 years (2022 to 2025), Denali Therapeutics Inc.'s business segments — research and development expense has grown at a 5.3% compound annual growth rate (CAGR), from $358.73M to $418.78M.
What does business segments — research and development expense mean?
The total aggregate cost of all research and development activities, including internal personnel, external collaborations, and overhead. This is a primary indicator of the company's commitment to advancing its clinical and preclinical pipeline. Investors use this to evaluate the company's burn rate and the scale of its scientific investment.

Ask your AI about Denali Therapeutics Inc.'s business segments — research and development expense.

Connect your AI assistant and compare it to peers, right in your chat.

Connect your AI
Harbor at dusk
Claude