Denali Therapeutics Inc. DNLI Return on invested capital

Return on invested capital at other companies

Eli LillyLLY

39.7%+10.3pp

Regeneron PharmaceuticalsREGN

10.3%-1.5pp

Ultragenyx PharmaceuticalRARE

-475.4%+443pp

uniQureQURE

-119%+424pp

Viridian Therapeutics, Inc.VRDN

-78.5%-6.2pp

Eton Pharmaceuticals, Inc.ETON

-45.1%-22.2pp

FAQ

What is Denali Therapeutics Inc.'s return on invested capital?

Denali Therapeutics Inc. (DNLI) reported return on invested capital of -67.9% in Q2 2026.

How has Denali Therapeutics Inc.'s return on invested capital changed year-over-year?

Denali Therapeutics Inc.'s return on invested capital decreased by 45.7% year-over-year, from -46.6% to -67.9%.

What is the long-term trend for Denali Therapeutics Inc.'s return on invested capital?

Over 5 years (2020 to 2025), Denali Therapeutics Inc.'s return on invested capital has grown at a 37.8% compound annual growth rate (CAGR), from 11.4% to -56.8%.

What does return on invested capital mean?

Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.