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Denali Therapeutics Inc. DNLI Return on invested capital

Return on invested capital at other companies

Eli Lilly logo
Eli LillyLLY
42%+16.6pp
Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
10.3%-2.0pp
Viking Therapeutics logo
Viking TherapeuticsVKTX
-59.2%-292pp
uniQure logo
uniQureQURE
-119%+424pp
Biogen logo
BiogenBIIB
7.8%-0.4pp
Dyne Therapeutics, Inc. logo
Dyne Therapeutics, Inc.DYN
-188.2%+14.8pp

Other financials

Income statement

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Revenue-
Operating income-$137.4M+5.6%
Net income-$128.4M+3.4%
EPS (diluted)-$0.69+11.5%

Balance sheet

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Cash & equivalents$390.7M+551%
Total debt$40.0M-22.3%
Total equity$926.1M-17.5%
Total assets$1.3B-0.4%

Cash flow

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Operating cash flow-$131.2M+0.2%
CapEx$2.5M-51.4%
Free cash flow-$133.7M+2.1%

Valuation

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Market cap$3.93B+54.2%

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-49.6%+34.2pp
Debt / equity0.0×
Current ratio9.3×-0.3×

Where this comes from

Calculated from Denali Therapeutics Inc.’s reported figures.

Based on trailing twelve months.

The official record: Denali Therapeutics Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s return on invested capital?
Denali Therapeutics Inc. (DNLI) reported return on invested capital of -64.8% in Q1 2026.
How has Denali Therapeutics Inc.'s return on invested capital changed year-over-year?
Denali Therapeutics Inc.'s return on invested capital decreased by 60.8% year-over-year, from -40.3% to -64.8%.
What is the long-term trend for Denali Therapeutics Inc.'s return on invested capital?
Over 5 years (2020 to 2025), Denali Therapeutics Inc.'s return on invested capital has grown at a 37.8% compound annual growth rate (CAGR), from 11.4% to -56.8%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.