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Denali Therapeutics Inc. DNLI Unrealized Gains on Investments

Unrealized Gains on Investments at other companies

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Other financials

Income statement

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Revenue$3.6M
Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

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Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

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Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

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Market cap$4B+97.6%
Enterprise value$3.83B+98.8%
P/S1,108.8×+1,104×

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 4:08 PM EDT
Fiscal quarter
Q4 FY2026
Calendar quarter
Q4 2026
Accession
0001714899-26-000097
Line itemAmortized CostUnrealized Holding GainsUnrealized Holding LossesAggregate Fair Value
U.S. government treasuries$409,364$20$(555)$408,829
Corporate debt securities100,34216(246)100,112
Total short-term marketable securities509,70636(801)508,941
Long-term marketable securities:
U.S. government treasuries164,059(658)163,401
Corporate debt securities66,328(195)66,133
Total long-term marketable securities230,387(853)229,534
Total$740,093$36$(1,654)$738,475

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s unrealized gains on investments?
Denali Therapeutics Inc. (DNLI) reported unrealized gains on investments of $36K in Q2 2026.
How has Denali Therapeutics Inc.'s unrealized gains on investments changed year-over-year?
Denali Therapeutics Inc.'s unrealized gains on investments decreased by 97.4% year-over-year, from $1.36M to $36K.
What is the long-term trend for Denali Therapeutics Inc.'s unrealized gains on investments?
Over 5 years (2020 to 2025), Denali Therapeutics Inc.'s unrealized gains on investments has grown at a 49.3% compound annual growth rate (CAGR), from $130K to $964K.
What does unrealized gains on investments mean?
The total unrealized gains on investments, typically related to available-for-sale securities.

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