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Other financials

Income statement

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Revenue$3.6M
Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

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Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

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Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

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Market cap$3.92B+88.3%
Enterprise value$3.76B+89.0%
P/S1,089×+1,084×

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 4:08 PM EDT
Fiscal quarter
Q4 FY2026
Calendar quarter
Q4 2026
Accession
0001714899-26-000097
Line itemThree Months Ended June 30, 2026Three Months Ended June 30, 2025Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Numerator:
Net loss$(127,553)$(124,119)$(256,000)$(257,089)
Denominator:
Weighted average number of:
Common stock shares outstanding158,982,722145,403,782158,645,833145,290,503
Pre-funded warrants28,331,77926,046,06528,331,77926,046,065
Total187,314,501171,449,847186,977,612171,336,568
Net loss per share$(0.68)$(0.72)$(1.37)$(1.50)

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s shares (diluted)?
Denali Therapeutics Inc. (DNLI) reported shares (diluted) of 187.3M in Q2 2026.
How has Denali Therapeutics Inc.'s shares (diluted) changed year-over-year?
Denali Therapeutics Inc.'s shares (diluted) increased by 9.3% year-over-year, from 171.4M to 187.3M.
What is the long-term trend for Denali Therapeutics Inc.'s shares (diluted)?
Over 4 years (2021 to 2025), Denali Therapeutics Inc.'s shares (diluted) has grown at a 9.1% compound annual growth rate (CAGR), from 485.4M to 687.7M.
What does shares (diluted) mean?
The weighted-average shares outstanding plus all potentially dilutive shares from stock options, RSUs, convertible securities, and warrants, using the treasury stock method.

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