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Illumina ILMN Q4 2025 Annual earnings

Reported February 5, 2026 · After market close

Revenue$1.2BBeat by $40.2M
EPS$1.35Beat by $0.11
Revenue estimate$1.1B
EPS estimate$1.24

Next report

Oct 29, 2026 (in 2 months)
Revenue estimate$1.2B
EPS estimate$1.38

Financials

Q4 2025

Income statement

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Revenue$1.2B+5.0%
Gross profit$759.0M+4.3%
Operating income$201.0M—
Net income$334.0M+79.6%
EPS (diluted)$2.16—

Balance sheet

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Cash & equivalents$1.4B+25.8%
Total debt$2.1B-3.3%
Total equity$2.7B+14.7%
Total assets$6.6B+5.4%

Cash flow

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Operating cash flow$321.0M-11.8%
CapEx$55.0M+89.7%
Free cash flow$266.0M-20.6%

Valuation & ratios

Valuation

as of 12/28/25
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Market cap$20.04B-5.4%
Enterprise value$20.68B-6.8%
P/E23.6×—
P/S4.6×-0.2×

Profitability

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Gross margin66.1%+0.6pp
Operating margin18.6%—
Net margin19.6%+12.3pp
FCF margin21.4%+5.2pp

Returns & leverage

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Return on equity33.4%+22.6pp
Debt / equity0.8×-0.1×
Current ratio2.1×+0.3×

Segments

By product

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Consumables$832.0M+6.8%
Service$169.0M+1.8%
Instruments$158.0M-0.6%

By segment

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Sequencing$1.1B+6.2%
Microarray$93.0M-7.0%

FAQ

When did Illumina report Q4 2025 earnings?
Illumina (ILMN) reported Q4 2025 earnings on February 5, 2026 after market close.
What were Illumina's Q4 2025 revenue and EPS?
Illumina reported revenue of $1.2B and eps of $1.35 for Q4 2025.
Did Illumina beat estimates in Q4 2025?
Revenue beat the consensus estimate of $1.1B by $40.2M. EPS beat the consensus estimate of $1.24 by $0.11.
How did Illumina's Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 5.0% from $1.1B a year earlier and eps grew 57.0% from $0.86.
Where can I find Illumina's Q4 2025 SEC filings?
You can read the 8-K earnings release (0001110803-26-000018) and the 10-K periodic report (0001110803-26-000024) directly on SEC EDGAR. The filing index links above go to sec.gov.