What are Illumina's profit margins?

Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.

Where do Illumina's ratios come from?

Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Illumina ILMN Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	265%-0.1pp	265.2%+0.6pp	264.5%+2.3pp	262.3%+4.5pp	257.7%+5.0pp
Net margin	84.7%+41.7pp	43%+47.5pp	-4.5%+52.5pp	-57%+98.1pp	-155.1%+6.4pp
Free cash flow margin	91%+2.0pp	89%+5.2pp	83.8%+10.9pp	72.9%+16.0pp	56.9%+12.1pp
Returns
Return on equity	166.4%+57.7pp	108.7%+63.5pp	45.2%+70.7pp	-25.4%+144pp	-169.7%-3.1pp
Return on assets	58.7%+25.3pp	33.4%+28.0pp	5.4%+31.2pp	-25.8%+54.8pp	-80.6%-0.1pp
Efficiency
Asset turnover	2.8×+0.2×	2.6×+0.1×	2.5×+0.2×	2.3×+0.2×	2.1×+0.1×
Liquidity
Current ratio	7.1×-0.1×	7.2×+0.3×	6.9×-1.0×	7.9×+0.7×	7.2×+0.1×
Quick ratio	6.2×+0.3×	5.9×+0.7×	5.1×-0.7×	5.8×+0.5×	5.3×+0.1×
Cash ratio	2.8×-0.1×	2.8×+0.2×	2.7×-0.4×	3×+0.2×	2.8×0.0×
Leverage
Debt-to-equity	3.1×-0.1×	3.2×-0.1×	3.4×-0.6×	4×-0.6×	4.6×+0.5×
Debt-to-assets	1.2×0.0×	1.3×0.0×	1.3×-0.2×	1.5×0.0×	1.5×+0.1×
Per Share
Book value per share	$64.67+4.0%	$62.19+4.2%	$59.66+3.8%	$57.48+10.3%	$52.13-28.9%
Valuation
Market capitalization	$67.97B+10.2%	$61.69B-1.8%	$62.85B-8.9%	$68.98B-3.0%	$71.09B-11.5%
Enterprise value	$71.26B+9.6%	$65.02B-2.3%	$66.53B-10.0%	$73.94B-2.9%	$76.15B-11.0%
Price / earnings	78×—	——	——	——	——
Price / sales	15.7×+1.4×	14.3×-0.2×	14.5×-1.3×	15.9×-0.4×	16.2×-2.0×
Price / book	26.9×+1.7×	25.2×-1.6×	26.8×-3.6×	30.4×-5.1×	35.6×+1.5×
EV / sales	16.4×+1.4×	15.1×-0.3×	15.4×-1.6×	17×-0.4×	17.4×-2.0×
Free cash flow yield	23.8%-1.8pp	25.6%+1.3pp	24.3%+4.2pp	20.1%+5.0pp	15.1%+5.3pp
Earnings yield	22.3%+12.2pp	10%+10.0pp	0%+12.5pp	-12.4%+27.0pp	-39.4%-1.8pp

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Questions, answered.

What are Illumina's profit margins?: Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.
Where do Illumina's ratios come from?: Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.