What are Illumina's profit margins?

Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.

Where do Illumina's ratios come from?

Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Illumina ILMN Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	265%+7.3pp	265.2%+12.4pp	264.5%+16.3pp	262.3%+16.5pp	257.7%+11.7pp
Net margin	84.7%+240pp	43%+205pp	-4.5%+155pp	-57%+91.4pp	-155.1%+18.4pp
Free cash flow margin	91%+34.1pp	89%+44.1pp	83.8%+48.9pp	72.9%+46.7pp	56.9%—
Returns
Return on equity	166.4%+336pp	108.7%+275pp	45.2%+201pp	-25.4%+108pp	-169.7%-63.1pp
Return on assets	58.7%+139pp	33.4%+114pp	5.4%+81.3pp	-25.8%+41.0pp	-80.6%-17.1pp
Efficiency
Asset turnover	2.8×+0.7×	2.6×+0.6×	2.5×+0.6×	2.3×+0.6×	2.1×+0.5×
Liquidity
Current ratio	7.1×-0.1×	7.2×+0.1×	6.9×-0.1×	7.9×+1.7×	7.2×+0.7×
Quick ratio	6.2×+0.9×	5.9×+0.7×	5.1×+0.1×	5.8×+1.3×	5.3×+0.5×
Cash ratio	2.8×0.0×	2.8×+0.1×	2.7×-0.1×	3×+0.6×	2.8×+0.1×
Leverage
Debt-to-equity	3.1×-1.4×	3.2×-0.8×	3.4×-0.2×	4×+1.3×	4.6×+2.9×
Debt-to-assets	1.2×-0.3×	1.3×-0.1×	1.3×0.0×	1.5×+0.4×	1.5×+0.5×
Per Share
Book value per share	$64.67+24.1%	$62.19-15.2%	$59.66-37.0%	$57.48-51.6%	$52.13-65.5%
Valuation
Market capitalization	$67.97B-4.4%	$61.69B-23.2%	$62.85B-22.7%	$68.98B-16.1%	$71.09B-25.4%
Enterprise value	$71.26B-6.4%	$65.02B-24.0%	$66.53B-23.3%	$73.94B-15.2%	$76.15B-24.2%
Price / earnings	78×—	——	——	——	——
Price / sales	15.7×-0.5×	14.3×-3.9×	14.5×-3.7×	15.9×-2.5×	16.2×-5.1×
Price / book	26.9×-8.6×	25.2×-8.8×	26.8×-2.2×	30.4×+7.5×	35.6×+19.7×
EV / sales	16.4×-0.9×	15.1×-4.3×	15.4×-4.1×	17×-2.5×	17.4×-5.1×
Free cash flow yield	23.8%+8.7pp	25.6%+15.8pp	24.3%+16.5pp	20.1%+14.2pp	15.1%—
Earnings yield	22.3%+61.7pp	10%+47.7pp	0%+37.2pp	-12.4%+22.3pp	-39.4%-9.0pp

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Questions, answered.

What are Illumina's profit margins?: Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.
Where do Illumina's ratios come from?: Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.