What is Insmed's pre-tax income (domestic)?

Insmed (INSM) reported pre-tax income (domestic) of -$279.62M in Q4 2025.

How has Insmed's pre-tax income (domestic) changed year-over-year?

Insmed's pre-tax income (domestic) decreased by 37.3% year-over-year, from -$203.63M to -$279.62M.

What is the long-term trend for Insmed's pre-tax income (domestic)?

Over 4 years (2021 to 2025), Insmed's pre-tax income (domestic) has grown at a 33.8% compound annual growth rate (CAGR), from -$348.85M to -$1.12B.

Other

Pre-Tax Income (Domestic)

Insmed Pre-Tax Income (Domestic) remained flat by 0.0% to -$279.62M in Q4 2025 compared to the prior quarter. Year-over-year, this metric declined by 37.3%, from -$203.63M to -$279.62M. Over 4 years (FY 2021 to FY 2025), Pre-Tax Income (Domestic) shows a downward trend with a 33.8% CAGR.

Analysis

StatementCash Flow Statement

SectionOther

First reportedQ1 2013

Last reportedQ4 2025Feb 19, 2026

Metric ID: other_income_loss_from_continuing_operations_before_inco_5322d6

Historical Data

5 years

	FY'21	FY'22	FY'23	FY'24	FY'25
Value	-$348.85M	-$406.26M	-$666.18M	-$814.53M	-$1.12B
YoY Change	—	-16.5%	-64.0%	-22.3%	-37.3%

Range-$1.12B – -$348.85M

CAGR+33.8%

Avg YoY Growth-35.0%

Median YoY Growth-29.8%

Current Streak4+ years decline

Pre-Tax Income (Domestic) at Other Companies

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Frequently Asked Questions

What is Insmed's pre-tax income (domestic)?: Insmed (INSM) reported pre-tax income (domestic) of -$279.62M in Q4 2025.
How has Insmed's pre-tax income (domestic) changed year-over-year?: Insmed's pre-tax income (domestic) decreased by 37.3% year-over-year, from -$203.63M to -$279.62M.
What is the long-term trend for Insmed's pre-tax income (domestic)?: Over 4 years (2021 to 2025), Insmed's pre-tax income (domestic) has grown at a 33.8% compound annual growth rate (CAGR), from -$348.85M to -$1.12B.