What are Lexicon Pharmaceuticals's profit margins?

Lexicon Pharmaceuticals (LXRX) runs a 99.5% gross margin and a -34.8% operating margin, with a -37.5% net margin.

Where do Lexicon Pharmaceuticals's ratios come from?

Every ratio is computed from Lexicon Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Lexicon Pharmaceuticals LXRX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	99.5%0.0pp	99.4%0.0pp	99.4%+0.2pp	99.2%+1.1pp	98%0.0pp
Operating margin	-34.8%+63.4pp	-98.2%-3.8pp	-94.4%+108pp	-202.6%+366pp	-568.6%+65.6pp
Net margin	-37.5%+63.6pp	-101.1%-4.3pp	-96.8%+110pp	-206.4%+362pp	-568%+76.7pp
Returns
Return on equity	-16%+23.7pp	-39.7%+6.2pp	-45.9%+19.4pp	-65.3%+20.8pp	-86.1%+81.6pp
Return on invested capital	-13.5%+20.1pp	-33.5%+4.0pp	-37.5%+15.0pp	-52.5%+23.8pp	-76.3%+32.6pp
Efficiency
Asset turnover	0.2×0.0×	0.2×-0.1×	0.3×+0.1×	0.2×+0.1×	0.1×0.0×
Liquidity
Current ratio	18.8×+13.9×	4.9×-0.8×	5.6×+1.5×	4.2×+1.9×	2.2×-3.2×
Leverage
Debt-to-equity	0.3×-0.3×	0.6×0.0×	0.5×+0.1×	0.5×-0.4×	0.9×+0.1×
Per Share
Book value per share	$0.51+71.1%	$0.30-10.4%	$0.33-7.1%	$0.36+4.8%	$0.34-25.5%
Valuation
Market capitalization	$986.12M+273%	$417.91M-14.8%	$490.59M+75.4%	$279.76M+67.9%	$166.58M-37.6%
Price / sales	14.2×+5.7×	8.4×+1.5×	6.9×+2.1×	4.8×-0.5×	5.3×-3.3×
Price / book	5×+2.8×	3.9×-0.2×	4.1×+1.9×	2.2×+0.8×	1.4×-0.5×

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Questions, answered.

What are Lexicon Pharmaceuticals's profit margins?: Lexicon Pharmaceuticals (LXRX) runs a 99.5% gross margin and a -34.8% operating margin, with a -37.5% net margin.
Where do Lexicon Pharmaceuticals's ratios come from?: Every ratio is computed from Lexicon Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.