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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
Profitability
Operating margin-27.7%+3.6pp-31.3%+10.2pp-41.5%+18.6pp-60.1%+73.9pp-134%
Net margin-27.3%+2.8pp-30.1%+9.0pp-39%+15.6pp-54.7%+68.7pp-123.4%
Returns
Return on equity-49.3%-6.9pp-42.5%-1.3pp-41.2%-4.9pp-36.3%+13.9pp-50.2%+30.2pp
Return on invested capital-46.7%-7.1pp-39.6%+5.2pp-44.8%+10.1pp-54.9%+29.1pp-84%-0.4pp
Efficiency
Asset turnover+0.2×0.8×+0.2×0.6×+0.1×0.5×+0.2×0.3×+0.1×
Liquidity
Current ratio3.5×-0.5×+0.6×3.4×-1.7×5.1×-0.8×5.9×-0.2×
Leverage
Debt-to-equity0.7×+0.1×0.6×0.0×0.6×+0.4×0.2×0.0×0.2×0.0×
Per Share
Book value per share$18.72-11.8%$21.21-3.3%$21.95-11.0%$24.65-2.6%$25.30-9.7%
Valuation
Market capitalization$12.01B-9.2%$13.23B+29.4%$10.22B+61.6%$6.33B-13.5%$7.31B+8.7%
Price / sales10.6×-3.2×13.8×0.0×13.8×+1.5×12.3×-10.8×23×
Price / book22.1×+0.2×21.9×+5.6×16.3×+7.2×9.1×-1.2×10.3×+1.4×

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Questions, answered.

What are Madrigal Pharmaceuticals, Inc.'s profit margins?
Madrigal Pharmaceuticals, Inc. (MDGL) runs a 96.5% gross margin and a -27.7% operating margin, with a -27.3% net margin.
Where do Madrigal Pharmaceuticals, Inc.'s ratios come from?
Every ratio is computed from Madrigal Pharmaceuticals, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.