Discontinued — last reported Q4 '25

Business Segments · Gross Profit

Single Reportable — Gross Profit

Natera, Inc. Single Reportable — Gross Profit increased by 15.9% to $445.43M in Q4 2025 compared to the prior quarter. Year-over-year, this metric grew by 48.7%, from $299.64M to $445.43M. Over 3 years (FY 2022 to FY 2025), Single Reportable — Gross Profit shows an upward trend with a 60.1% CAGR. This is a positive signal — higher values indicate stronger performance for this metric.

Analysis

StatementSegment
CategoryProfitability
SignalHigher is better
VolatilityModerate
First reportedQ1 2022
Last reportedQ4 2025
Rolls up toGross Profit

How to read this metric

An increase suggests improved operational efficiency or higher pricing power, whereas a decrease may indicate rising input costs or pricing pressure in the diagnostic market.

Detailed definition

Gross profit represents the revenue remaining after deducting the direct costs associated with providing diagnostic test...

Peer comparison

Standard gross profit metric used across the healthcare and diagnostics industry to assess core operational performance.

Metric ID: ntra_segment_single_reportable_gross_profit

Historical Data

16 periods
 Q1 '22Q2 '22Q3 '22Q4 '22Q1 '23Q2 '23Q3 '23Q4 '23Q1 '24Q2 '24Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25
Value$90.99M$90.99M$90.99M$90.99M$123.19M$123.19M$123.19M$123.19M$208.60M$243.17M$271.75M$299.64M$316.77M$346.60M$384.38M$445.43M
QoQ Change+0.0%+0.0%+0.0%+35.4%+0.0%+0.0%+0.0%+69.3%+16.6%+11.8%+10.3%+5.7%+9.4%+10.9%+15.9%
YoY Change+35.4%+35.4%+35.4%+35.4%+69.3%+97.4%+120.6%+143.2%+51.9%+42.5%+41.4%+48.7%
Range$90.99M$445.43M
CAGR+52.7%
Avg YoY Growth+63.1%
Median YoY Growth+45.6%
Current Streak15+ quarters growth

Frequently Asked Questions

What is Natera, Inc.'s single reportable — gross profit?
Natera, Inc. (NTRA) reported single reportable — gross profit of $445.43M in Q4 2025.
How has Natera, Inc.'s single reportable — gross profit changed year-over-year?
Natera, Inc.'s single reportable — gross profit increased by 48.7% year-over-year, from $299.64M to $445.43M.
What is the long-term trend for Natera, Inc.'s single reportable — gross profit?
Over 3 years (2022 to 2025), Natera, Inc.'s single reportable — gross profit has grown at a 60.1% compound annual growth rate (CAGR), from $363.97M to $1.49B.
What does single reportable — gross profit mean?
The profit earned from core business activities after subtracting the direct costs of providing those services.