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Prime Medicine

PRME

Prime Medicine is a biotechnology company pioneering Prime Editing, a next-generation gene editing technology designed to precisely rewrite DNA sequences without causing double-stranded breaks.

Market cap
$543.66M+3.1%
Net income-$198.4M+1.8%
Free cash flow-$158.7M+19.0%
EPS (diluted)-$1.25+22.4%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 6, 2026 (In 1 week)
Revenue estimate$2.3M
EPS estimate-$0.24

Financials

Q1 2026

Income statement

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Operating income-$50.7M+3.3%
Net income-$49.1M+5.3%
EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%
Total debt$114.5M-5.5%
Total equity$76.7M-28.3%
Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%
CapEx$214.0K-91.2%
Free cash flow-$42.9M+16.3%

Valuation & ratios

Valuation

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Market cap$543.66M+3.1%
Enterprise value$580.37M-3.6%

Returns & leverage

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Return on equity-216.1%+1,519pp
Debt / equity1.5×+0.4×
Current ratio3.8×-1.0×

Segments

By segment

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Reportable Segment$856.0K-41.1%

Competitors

Profile

Prime Medicine is a biotechnology company pioneering Prime Editing, a next-generation gene editing technology designed to precisely rewrite DNA sequences without causing double-stranded breaks. The company develops curative genetic medicines for diseases driven by genetic alterations, focusing on liver-directed in vivo therapies and ex vivo cell engineering. Their modular platform is engineered to accelerate drug development by utilizing shared delivery systems and editor components across multiple therapeutic indications.

Competitive position

Prime Medicine is a leader in the emerging field of Prime Editing, positioning itself as a more precise and versatile alternative to first-generation CRISPR nucleases and base editors.

GeographiesUnited States, Europe, Japan
Customer segmentsPharmaceutical companies, Rare disease patients
Business modelR&D intensive, Licensing and Royalties, Collaborative Development
SuppliersAcademic research institutions, Contract Manufacturing Organizations (CMOs), Contract Testing Organizations, Specialized raw material suppliers
CustomersBiopharmaceutical companies, Specialty pharmacies, Hospitals and infusion centers
Listed2022
Employees234.0
CEOAllan Reine
FilingsSEC EDGAR

Questions, answered.

What is Prime Medicine's market cap?
Prime Medicine (PRME) has a market capitalization of $543.7M and trades on NASDAQ.
Who are Prime Medicine's competitors?
Prime Medicine's key competitors include Intellia Therapeutics, Editas Medicine, CRISPR Therapeutics, and others. These companies compete in similar markets and product categories.
Who does Prime Medicine partner with?
Prime Medicine's notable partners include Bristol-Myers Squibb, Beam Therapeutics, Broad Institute, and others.
Where is Prime Medicine headquartered?
Prime Medicine is headquartered in United States of America and employs approximately 234 people. It has been publicly traded since 2022.