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Prime Medicine PRME Return on equity

Return on equity at other companies

Eli Lilly logo
Eli LillyLLY
107.6%+29.9pp
Vertex Pharmaceuticals logo
Vertex PharmaceuticalsVRTX
24.2%
Intellia Therapeutics logo
Intellia TherapeuticsNTLA
-56.3%-1.5pp
CRISPR Therapeutics logo
CRISPR TherapeuticsCRSP
-31.2%+43.7pp
Beam Therapeutics logo
Beam TherapeuticsBEAM
-47.1%
Regenxbio logo
RegenxbioRGNX
-196.4%-288pp

Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$50.7M+3.3%
Net income-$49.1M+5.3%
EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%
Total debt$114.5M-5.5%
Total equity$76.7M-28.3%
Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%
CapEx$214.0K-91.2%
Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%
Enterprise value$611.08M+113%
P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Debt / equity1.5×+0.4×
Current ratio3.8×-1.0×

Where this comes from

Calculated from Prime Medicine’s reported figures.

Based on trailing twelve months.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's return on equity?
Prime Medicine (PRME) reported return on equity of -216.1% in Q1 2026.
How has Prime Medicine's return on equity changed year-over-year?
Prime Medicine's return on equity decreased by 87.5% year-over-year, from -115.2% to -216.1%.
What is the long-term trend for Prime Medicine's return on equity?
Over 2 years (2023 to 2025), Prime Medicine's return on equity has grown at a 29.0% compound annual growth rate (CAGR), from -88.2% to -146.8%.
What does return on equity mean?
Trailing-twelve-month net income divided by average shareholders' equity (average of the start and end of the trailing-twelve-month window). Measures the profit generated on each dollar of shareholder capital.