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Prime Medicine PRME Operating margin

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Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$43.3M+18.9%
Net income-$42.1M+19.9%
EPS (diluted)-$0.24+41.5%

Balance sheet

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Cash & equivalents$61.1M-9.4%
Total debt$112.5M-6.1%
Total equity$39.8M-34.6%
Total assets$249.0M-10.7%

Cash flow

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Operating cash flow-$41.0M+0.9%
CapEx$46.0K-97.1%
Free cash flow-$41.1M+4.4%

Valuation

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Market cap$558.64M-10.7%
Enterprise value$609.98M-10.0%

Profitability

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Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Return on equity-373.3%-1,281pp
Debt / equity2.8×+0.9×
Current ratio3.1×-0.5×

Where this comes from

Calculated from Prime Medicine’s reported figures.

Based on trailing twelve months.

The source filing: Prime Medicine’s 10-Q, filed August 6, 2026. Open the filing →

Filed
Aug 6, 2026, 8:03 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001628280-26-053883

FAQ

What is Prime Medicine's operating margin?
Prime Medicine (PRME) reported operating margin of -4,498.1% in Q4 2025.
How has Prime Medicine's operating margin changed year-over-year?
Prime Medicine's operating margin increased by 33.7% year-over-year, from -6,787.4% to -4,498.1%.
What is the long-term trend for Prime Medicine's operating margin?
Over 2 years (2020 to 2025), Prime Medicine's operating margin has grown at a 1485.7% compound annual growth rate (CAGR), from -17.9% to -4,498.1%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.

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