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Prime Medicine PRME Total Revenue

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Segments

By segment

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Reportable Segment$1.15M+3.5%

Other financials

Income statement

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Operating income-$43.3M+18.9%
Net income-$42.1M+19.9%
EPS (diluted)-$0.24+41.5%

Balance sheet

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Cash & equivalents$61.1M-9.4%
Total debt$112.5M-6.1%
Total equity$39.8M-34.6%
Total assets$249.0M-10.7%

Cash flow

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Operating cash flow-$41.0M+0.9%
CapEx$46.0K-97.1%
Free cash flow-$41.1M+4.4%

Valuation

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Market cap$558.64M-10.7%
Enterprise value$609.98M-10.0%

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Return on equity-373.3%-1,281pp
Debt / equity2.8×+0.9×
Current ratio3.1×-0.5×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The source filing: Prime Medicine’s 10-K, filed March 3, 2026.

Filed
Mar 3, 2026, 8:19 AM EST
Fiscal year
FY2025
Accession
0001628280-26-013569
(in thousands, except share and per share amounts)Year Ended December 31, 2025Year Ended December 31, 2024
Revenue:
Collaboration revenue — related party$4,586$1,609
Collaboration revenue461,374
Total revenue4,6322,983
Operating expenses:
Research and development160,636155,289
General and administrative52,34650,161
Total operating expenses212,982205,450

Item 16. Form 10-K Summary

FAQ

What is Prime Medicine's total revenue?
Prime Medicine (PRME) reported total revenue of $838K in Q4 2025.
How has Prime Medicine's total revenue changed year-over-year?
Prime Medicine's total revenue decreased by 61.6% year-over-year, from $2.18M to $838K.
What does total revenue mean?
The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.

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