What is Vertex Pharmaceuticals's total revenue?

Vertex Pharmaceuticals (VRTX) reported total revenue of $2.99B in Q1 2026.

How has Vertex Pharmaceuticals's total revenue changed year-over-year?

Vertex Pharmaceuticals's total revenue increased by 7.8% year-over-year, from $2.77B to $2.99B.

What is the long-term trend for Vertex Pharmaceuticals's total revenue?

Over 4 years (2021 to 2025), Vertex Pharmaceuticals's total revenue has grown at a 12.2% compound annual growth rate (CAGR), from $7.57B to $12B.

What does total revenue mean?

The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.

Vertex Pharmaceuticals VRTX Total Revenue

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$127.2M+55.6%

Agios PharmaceuticalsAGIO

$20.75M+138%

AbbVieABBV

$15B+12.4%

4D Molecular TherapeuticsFDMT

$3.05M+21,664%

Beam TherapeuticsBEAM

$31.74M+325%

Segments

By product

See full

TRIKAFTA/KAFTRIO$2.35B-7.1%

ALYFTREK$424.4M+687%

Other CF product revenues$135.9M-12.5%

CASGEVY$42.9M—

JOURNAVX$29M—

By geography

See full

Europe$950M+14.9%

Other$261M-6.8%

By segment

See full

Pharmaceuticals$2.99B+7.8%

Other financials

Income statement

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Gross profit$2.6B+7.8%

Operating income$1.1B+80.6%

Net income$1.0B+59.6%

EPS (diluted)$4.02+61.4%

Balance sheet

See full

Cash & equivalents$5.5B+17.5%

Total debt$2.0B+20.5%

Total equity$19.4B+17.4%

Total assets$26.5B+15.8%

Cash flow

See full

Operating cash flow$1.4B+74.4%

CapEx$133.4M+228%

Free cash flow$1.3B+66.4%

Valuation

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Market cap$121.87B+7.6%

Enterprise value$118.35B+7.4%

P/E28.1×—

P/S10×-0.2×

Profitability

See full

Gross margin86.2%+0.2pp

Operating margin38.3%—

Net margin35.5%—

FCF margin30.4%+20.2pp

Returns & leverage

See full

Return on equity24.2%—

Debt / equity0.1×0.0×

Current ratio3×+0.4×

Where this comes from

Reported directly by Vertex Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The official record: Vertex Pharmaceuticals’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Vertex Pharmaceuticals's total revenue?: Vertex Pharmaceuticals (VRTX) reported total revenue of $2.99B in Q1 2026.
How has Vertex Pharmaceuticals's total revenue changed year-over-year?: Vertex Pharmaceuticals's total revenue increased by 7.8% year-over-year, from $2.77B to $2.99B.
What is the long-term trend for Vertex Pharmaceuticals's total revenue?: Over 4 years (2021 to 2025), Vertex Pharmaceuticals's total revenue has grown at a 12.2% compound annual growth rate (CAGR), from $7.57B to $12B.
What does total revenue mean?: The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.