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Vertex Pharmaceuticals VRTX TRIKAFTA/KAFTRIO — Product revenues, net

Other product segments

ALYFTREK
$573.6M+266%
Other CF product revenues
$135.9M-12.5%
CASGEVY
$76.4M
JOURNAVX
$49.6M

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Other financials

Income statement

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Revenue$3.3B+12.5%
Gross profit$2.8B+11.2%
Operating income$1.2B+8.3%
Net income$1.1B+6.5%
EPS (diluted)$4.31+8.0%

Balance sheet

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Cash & equivalents$7.9B+57.6%
Total debt$2.0B+29.5%
Total equity$20.2B+17.9%
Total assets$27.4B+14.1%

Cash flow

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Operating cash flow$1.4B+74.4%
CapEx$133.4M+228%
Free cash flow$1.3B+66.4%

Valuation

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Market cap$122.68B+24.1%
Enterprise value$116.81B+22.4%
P/E27.9×
P/S9.8×+1.1×

Profitability

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Gross margin86%-0.1pp
Operating margin38%
Net margin35%
FCF margin30.4%+20.2pp

Returns & leverage

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Return on equity23.5%
Debt / equity0.1×0.0×
Current ratio3.2×+0.7×

Where this comes from

Reported directly by Vertex Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The source filing: Vertex Pharmaceuticals’s 8-K, filed August 3, 2026. Open the filing →

Filed
Aug 3, 2026, 4:09 PM EDT
Accession
0000875320-26-000256

FAQ

What is Vertex Pharmaceuticals's TRIKAFTA/KAFTRIO — product revenues, net?
Vertex Pharmaceuticals (VRTX) reported TRIKAFTA/KAFTRIO — product revenues, net of $2.5B in Q2 2026.
How has Vertex Pharmaceuticals's TRIKAFTA/KAFTRIO — product revenues, net changed year-over-year?
Vertex Pharmaceuticals's TRIKAFTA/KAFTRIO — product revenues, net decreased by 2.1% year-over-year, from $2.55B to $2.5B.
What is the long-term trend for Vertex Pharmaceuticals's TRIKAFTA/KAFTRIO — product revenues, net?
Over 4 years (2021 to 2025), Vertex Pharmaceuticals's TRIKAFTA/KAFTRIO — product revenues, net has grown at a 16.0% compound annual growth rate (CAGR), from $5.7B to $10.31B.
What does TRIKAFTA/KAFTRIO — product revenues, net mean?
This metric represents the net sales generated from the company's primary cystic fibrosis therapeutic franchise after accounting for returns, discounts, and rebates. It serves as the core revenue driver for the business, reflecting the market adoption and patient utilization of the company's flagship small-molecule treatment portfolio. Monitoring this figure provides insight into the commercial success and competitive positioning of the company's most critical therapeutic asset.

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