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Vertex Pharmaceuticals VRTX Other CF product revenues — Product revenues, net

Other product segments

TRIKAFTA/KAFTRIO
$2.5B-2.1%
ALYFTREK
$573.6M+266%
CASGEVY
$76.4M
JOURNAVX
$49.6M

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Other financials

Income statement

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Revenue$3.3B+12.5%
Gross profit$2.8B+11.2%
Operating income$1.2B+8.3%
Net income$1.1B+6.5%
EPS (diluted)$4.31+8.0%

Balance sheet

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Cash & equivalents$7.9B+57.6%
Total debt$2.0B+29.5%
Total equity$20.2B+17.9%
Total assets$27.4B+14.1%

Cash flow

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Operating cash flow$1.4B+74.4%
CapEx$133.4M+228%
Free cash flow$1.3B+66.4%

Valuation

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Market cap$122.68B+24.1%
Enterprise value$116.81B+22.4%
P/E27.9×
P/S9.8×+1.1×

Profitability

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Gross margin86%-0.1pp
Operating margin38%
Net margin35%
FCF margin30.4%+20.2pp

Returns & leverage

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Return on equity23.5%
Debt / equity0.1×0.0×
Current ratio3.2×+0.7×

Where this comes from

Reported directly by Vertex Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The source filing: Vertex Pharmaceuticals’s 10-Q, filed May 5, 2026.

Filed
May 5, 2026, 4:08 PM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0000875320-26-000173
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
(in millions)
TRIKAFTA/KAFTRIO$2,354.7$2,535.5
ALYFTREK424.453.9
Other CF product revenues (1)135.9155.3
Total CF product revenues, net2,915.02,744.7
CASGEVY42.914.2
JOURNAVX29.01.3
Total product revenues, net$2,986.9$2,760.2

Item 1. Financial Statements (unaudited)

FAQ

What is Vertex Pharmaceuticals's other CF product revenues — product revenues, net?
Vertex Pharmaceuticals (VRTX) reported other CF product revenues — product revenues, net of $135.9M in Q1 2026.
How has Vertex Pharmaceuticals's other CF product revenues — product revenues, net changed year-over-year?
Vertex Pharmaceuticals's other CF product revenues — product revenues, net decreased by 12.5% year-over-year, from $155.3M to $135.9M.
What is the long-term trend for Vertex Pharmaceuticals's other CF product revenues — product revenues, net?
Over 2 years (2022 to 2025), Vertex Pharmaceuticals's other CF product revenues — product revenues, net has grown at a -19.6% compound annual growth rate (CAGR), from $1.24B to $804.6M.
What does other CF product revenues — product revenues, net mean?
This metric represents the net revenue generated from secondary or non-core pharmaceutical product lines outside of the company's primary therapeutic franchises. It captures the financial contribution of smaller, emerging, or legacy assets that are not categorized within the firm's main revenue-driving segments. Monitoring this figure helps investors assess the diversification of the product portfolio and the commercial success of secondary pipeline assets.

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