What are Rhythm Pharmaceuticals, Inc.'s profit margins?

Rhythm Pharmaceuticals, Inc. (RYTM) runs a 89.4% gross margin and a -90.9% operating margin, with a -93.3% net margin.

Where do Rhythm Pharmaceuticals, Inc.'s ratios come from?

Every ratio is computed from Rhythm Pharmaceuticals, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Rhythm Pharmaceuticals, Inc. RYTM Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	89.4%-0.3pp	89.7%+0.3pp	89.4%+0.2pp	89.2%-0.4pp	89.6%-0.1pp
Operating margin	-90.9%+10.3pp	-101.2%+5.6pp	-106.8%+6.7pp	-113.5%+12.6pp	-126.1%+77.9pp
Net margin	-93.3%+10.2pp	-103.6%+6.7pp	-110.3%+6.8pp	-117.1%+6.1pp	-123.3%+77.0pp
Returns
Return on equity	-285.8%-41.3pp	-244.5%-4.1pp	-240.4%—	——	-419%-147pp
Return on assets	-48.9%-3.8pp	-45.1%-0.9pp	-44.2%+4.3pp	-48.5%+3.8pp	-52.3%+19.6pp
Return on invested capital	-197.9%-40.0pp	-157.9%—	——	——	-967.9%-766pp
Efficiency
Asset turnover	0.5×+0.1×	0.4×0.0×	0.4×0.0×	0.4×0.0×	0.4×+0.1×
Inventory turnover	1×+0.1×	0.9×-0.2×	1×-0.1×	1.1×+0.1×	1×0.0×
Liquidity
Current ratio	4.2×-0.2×	4.4×-0.3×	4.7×+2.0×	2.8×-0.5×	3.3×+0.1×
Quick ratio	3.9×-0.3×	4.2×-0.4×	4.5×+1.9×	2.6×-0.5×	3.1×+0.1×
Cash ratio	0.6×+0.1×	0.5×0.0×	0.5×-0.5×	1×+0.1×	0.9×+0.2×
Leverage
Debt-to-equity	0.9×+0.1×	0.8×0.0×	0.8×—	——	6×+0.8×
Debt-to-assets	0.3×0.0×	0.2×0.0×	0.2×-0.1×	0.3×0.0×	0.3×0.0×
Interest coverage	-10×-0.7×	-9.3×-0.6×	-8.7×-0.6×	-8.1×+0.2×	-8.3×+4.9×
Per Share
Book value per share	$1.81-15.5%	$2.14-4.7%	$2.25+1,301%	-$0.19-162%	$0.30-15.6%
Valuation
Market capitalization	$5.94B-16.9%	$7.14B+6.5%	$6.71B+65.6%	$4.05B+20.9%	$3.35B-2.7%
Enterprise value	$5.99B-16.8%	$7.2B+6.4%	$6.77B+68.0%	$4.03B+20.0%	$3.36B-3.1%
Price / sales	27.3×-10.3×	37.6×-0.8×	38.5×+12.6×	25.9×+1.4×	24.5×-2.0×
Price / book	48.3×-3.0×	51.4×+6.3×	45.1×—	——	176.8×+18.4×
EV / sales	27.6×-10.4×	38×-0.9×	38.8×+13.1×	25.8×+1.3×	24.5×-2.1×
Earnings yield	-3.4%-0.7pp	-2.8%+0.1pp	-2.9%+1.7pp	-4.5%+0.5pp	-5%+2.5pp

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Questions, answered.

What are Rhythm Pharmaceuticals, Inc.'s profit margins?: Rhythm Pharmaceuticals, Inc. (RYTM) runs a 89.4% gross margin and a -90.9% operating margin, with a -93.3% net margin.
Where do Rhythm Pharmaceuticals, Inc.'s ratios come from?: Every ratio is computed from Rhythm Pharmaceuticals, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.