What is Stoke Therapeutics, Inc.'s pre-tax income?

Stoke Therapeutics, Inc. (STOK) reported pre-tax income of -$50M in Q1 2026.

How has Stoke Therapeutics, Inc.'s pre-tax income changed year-over-year?

Stoke Therapeutics, Inc.'s pre-tax income decreased by 143.8% year-over-year, from $114.16M to -$50M.

What does pre-tax income mean?

Total income from all sources — operating income plus non-operating items like interest income, investment gains, and other income — before the provision for income taxes.

Stoke Therapeutics, Inc. STOK Pre-Tax Income

Pre-Tax Income at other companies

Ionis PharmaceuticalsIONS

-$92.31M+37.1%

Jazz PharmaceuticalsJAZZ

$299.2M+372%

Xenon PharmaceuticalsXENE

-$104.87M-62.3%

Harmony Biosciences Holdings, Inc.HRMY

$39.69M-30.6%

Nuvation BioNUVB

$5.4M+110%

Septerna, Inc.SEPN

-$8.3M+61.4%

Other financials

Income statement

See full

Revenue$6.2M-96.1%

Operating income-$53.4M-148%

Net income-$50.0M-144%

EPS (diluted)-$0.79-142%

Balance sheet

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Cash & equivalents$155.7M-43.4%

Total debt$3.4M-42.5%

Total equity$394.9M+12.8%

Total assets$443.3M+8.9%

Cash flow

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Operating cash flow-$60.6M-146%

CapEx$353.0K+132%

Free cash flow-$60.9M-146%

Valuation

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Market cap$1.94B+436%

Enterprise value$1.79B+1,855%

P/S60.4×+58.5×

Profitability

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Operating margin-577.5%-597pp

Net margin-529.2%-556pp

FCF margin36.2%+18.4pp

Returns & leverage

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Return on equity-45.6%-66.1pp

Debt / equity0×0.0×

Current ratio9×+0.6×

Where this comes from

Reported directly by Stoke Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest.

The official record: Stoke Therapeutics, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Stoke Therapeutics, Inc.'s pre-tax income?: Stoke Therapeutics, Inc. (STOK) reported pre-tax income of -$50M in Q1 2026.
How has Stoke Therapeutics, Inc.'s pre-tax income changed year-over-year?: Stoke Therapeutics, Inc.'s pre-tax income decreased by 143.8% year-over-year, from $114.16M to -$50M.
What does pre-tax income mean?: Total income from all sources — operating income plus non-operating items like interest income, investment gains, and other income — before the provision for income taxes.