What is Stoke Therapeutics, Inc.'s net debt / EBITDA?

Stoke Therapeutics, Inc. (STOK) reported net debt / EBITDA of -2.8× in Q3 2025.

What does net debt / EBITDA mean?

Net debt (total debt minus cash) divided by trailing-twelve-month EBITDA. Expresses leverage in years — roughly how long it would take to repay net debt out of operating cash earnings.

Stoke Therapeutics, Inc. STOK Net debt / EBITDA

Net debt / EBITDA at other companies

Jazz PharmaceuticalsJAZZ

5.6×-2.2×

Harmony Biosciences Holdings, Inc.HRMY

-2×+1.3×

Roivant SciencesROIV

-0×—

Arrowhead ResearchARWR

-0.3×—

ALN

Alnylam PharmaceuticalsALNY

-1.8×—

Royalty PharmaRPRX

5.2×+1.4×

Other financials

Income statement

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Revenue$6.2M-96.1%

Operating income-$53.4M-148%

Net income-$50.0M-144%

EPS (diluted)-$0.79-142%

Balance sheet

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Cash & equivalents$155.7M-43.4%

Total debt$3.4M-42.5%

Total equity$394.9M+12.8%

Total assets$443.3M+8.9%

Cash flow

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Operating cash flow-$60.6M-146%

CapEx$353.0K+132%

Free cash flow-$60.9M-146%

Valuation

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Market cap$1.94B+436%

Enterprise value$1.79B+1,855%

P/S60.4×+58.5×

Profitability

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Operating margin-577.5%-597pp

Net margin-529.2%-556pp

FCF margin36.2%+18.4pp

Returns & leverage

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Return on equity-45.6%-66.1pp

Debt / equity0×0.0×

Current ratio9×+0.6×

Where this comes from

Calculated from Stoke Therapeutics, Inc.’s reported figures.

net debt/ebitda=-2.8×

Based on the most recent quarter.

The official record: Stoke Therapeutics, Inc.’s 10-Q, filed November 4, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Stoke Therapeutics, Inc.'s net debt / EBITDA?: Stoke Therapeutics, Inc. (STOK) reported net debt / EBITDA of -2.8× in Q3 2025.
What does net debt / EBITDA mean?: Net debt (total debt minus cash) divided by trailing-twelve-month EBITDA. Expresses leverage in years — roughly how long it would take to repay net debt out of operating cash earnings.