What is Talphera, Inc.'s net margin?

Talphera, Inc. (TLPH) reported net margin of -1,425,300% in Q1 2026.

How has Talphera, Inc.'s net margin changed year-over-year?

Talphera, Inc.'s net margin decreased by 3205.3% year-over-year, from -43,122.2% to -1,425,300%.

What is the long-term trend for Talphera, Inc.'s net margin?

Over 3 years (2020 to 2025), Talphera, Inc.'s net margin has grown at a 309.1% compound annual growth rate (CAGR), from -745.6% to -51,035.7%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Talphera, Inc. TLPH Net margin

Net margin at other companies

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-9.7%+62.5pp

AMP

Amphastar PharmaceuticalsAMPH

11%-8.4pp

Syndax PharmaceuticalsSNDX

-111.9%-51.5pp

Royalty PharmaRPRX

33.9%-14.4pp

PTH

Pelthos Therapeutics Inc.PTHS

-186.2%—

XOMA CorporationXOMA

69.6%+64.0pp

Other financials

Income statement

See full

Revenue--100%

Gross profit-$1.9M-52.7%

Operating income-$3.9M-35.4%

Net income-$2.6M+1.4%

EPS (diluted)-$0.10+37.5%

Balance sheet

See full

Cash & equivalents$3.8M-29.0%

Total debt$3.4M-79.7%

Total equity$18.5M+230%

Total assets$30.2M+101%

Cash flow

See full

Operating cash flow-$3.4M+2.0%

CapEx-—

Free cash flow-$2.3M+42.9%

Valuation

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Market cap$53.46M+493%

P/S53,456.6×+53,123×

Profitability

See full

Gross margin-127.7%-136pp

Operating margin-1,451,600%-1,507,145pp

FCF margin-5,116.7%-6,779pp

Returns & leverage

See full

Return on equity-118.4%+15.4pp

Debt / equity0.2×—

Current ratio5.3×+2.2×

Where this comes from

Calculated from Talphera, Inc.’s reported figures.

net income/total revenue=-1,425,300%

Based on trailing twelve months.

The official record: Talphera, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Talphera, Inc.'s net margin?: Talphera, Inc. (TLPH) reported net margin of -1,425,300% in Q1 2026.
How has Talphera, Inc.'s net margin changed year-over-year?: Talphera, Inc.'s net margin decreased by 3205.3% year-over-year, from -43,122.2% to -1,425,300%.
What is the long-term trend for Talphera, Inc.'s net margin?: Over 3 years (2020 to 2025), Talphera, Inc.'s net margin has grown at a 309.1% compound annual growth rate (CAGR), from -745.6% to -51,035.7%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.