What are 10x Genomics, Inc.'s profit margins?

10x Genomics, Inc. (TXG) runs a 69.6% gross margin and a -6.1% operating margin, with a -3.5% net margin.

Where do 10x Genomics, Inc.'s ratios come from?

Every ratio is computed from 10x Genomics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

10x Genomics, Inc. TXG Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	69.6%+0.6pp	69.1%+0.2pp	68.8%-0.7pp	69.5%+1.1pp	68.4%+0.5pp
Operating margin	-6.1%+3.4pp	-9.5%+4.7pp	-14.2%+1.4pp	-15.6%+12.0pp	-27.6%+4.3pp
Net margin	-3.5%+3.2pp	-6.8%+5.1pp	-11.9%+1.2pp	-13.1%+12.0pp	-25.1%+4.8pp
Returns
Return on equity	-3%+2.8pp	-5.8%+4.3pp	-10.1%+1.2pp	-11.3%+10.7pp	-22%+3.1pp
Return on invested capital	-9.5%+4.8pp	-14.3%+7.2pp	-21.5%+1.0pp	-22.4%+17.4pp	-39.9%+2.2pp
Efficiency
Asset turnover	0.7×0.0×	0.7×0.0×	0.7×0.0×	0.7×0.0×	0.7×0.0×
Liquidity
Current ratio	5.9×+1.4×	4.5×0.0×	4.5×-1.4×	5.8×+0.5×	5.4×+0.4×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Per Share
Book value per share	$6.35-0.6%	$6.38+2.0%	$6.26+0.7%	$6.21+7.7%	$5.77-2.2%
Valuation
Market capitalization	$2.71B+31.4%	$2.06B+41.8%	$1.46B+8.5%	$1.34B+25.6%	$1.07B-38.6%
Price / sales	4.2×+1.0×	3.2×+0.9×	2.3×+0.2×	2.1×+0.4×	1.7×-1.1×
Price / book	3.3×+0.7×	2.6×+0.7×	1.9×+0.1×	1.7×+0.2×	1.5×-0.9×

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Questions, answered.

What are 10x Genomics, Inc.'s profit margins?: 10x Genomics, Inc. (TXG) runs a 69.6% gross margin and a -6.1% operating margin, with a -3.5% net margin.
Where do 10x Genomics, Inc.'s ratios come from?: Every ratio is computed from 10x Genomics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.